Deep Learning MR Image Standardization Across Vendors

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Solution Overview

Problem

Radiologists face challenges in comparing sequential imaging studies acquired on different magnetic resonance (MR) hardware systems due to varying contrast and distortions, making clinical imaging trials more complex when multiple vendor scanners are involved.

Innovation Solution

The development of methods and systems that use deep learning to transform MR images from one vendor's style to another or to a standardized MR style, preserving anatomical information while adjusting contrast, resolution, and image distortion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If MR images are acquired using different vendor scanners, then more imaging options and hardware availability are provided, but image contrast and distortion vary making comparison challenging

Engineering Contradiction:
Improvehardware availabilityVSAvoidimage comparison accuracy
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent introduces a deep learning-based image transformation system as an intermediary that converts images from different vendor scanners into a standardized target style. This mediator processes the varying contrast and distortion characteristics of different vendors' images, transforming them into a unified representation that enables accurate comparison while preserving the ability to use diverse hardware platforms

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system changes the stylistic parameters of MR images (contrast, distortion, intensity distribution) through deep learning transformation. By learning the mapping between different vendor-specific image styles and a standardized target style, the system transforms images to have consistent parameters across vendors, enabling accurate comparison while maintaining hardware diversity

Inventive Principle:
Principle #35Parameter changes

2Productivity

If multiple vendor scanners are used in clinical imaging trials, then scanner availability and patient access improve, but image standardization and quantifiable comparison become more difficult

Engineering Contradiction:
Improvepatient accessVSAvoidimage standardization
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system performs preliminary image style transformation before clinical analysis and comparison. By pre-processing images from multiple vendors to a standardized target style using deep learning, the system establishes uniformity in advance, allowing subsequent clinical workflows to proceed with images that are already standardized, thus maintaining both high patient access and image standardization

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If deep learning transformation is applied to MR images, then image style standardization and diagnostic accuracy improve, but processing time and computational complexity increase

Engineering Contradiction:
Improvediagnostic accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The deep learning transformation model is trained in advance on large datasets of multi-vendor images. Once trained, the model can rapidly transform new images to the target style. This preliminary training phase separates the computationally intensive learning process from the actual clinical application, allowing fast inference during patient workflows while still achieving high diagnostic accuracy through the learned transformations

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12282856B2Systems and methods for magnetic resonance imaging standardization using deep learning
Publication Date: 2025.04.22 SUBTLE MEDICAL INC
  • US12282856B2 patent drawing
  • US12282856B2 patent drawing
  • US12282856B2 patent drawing

AI summary

A computer-implemented method for transforming magnetic resonance (MR) imaging across multiple vendors is provided. The method comprises: obtaining a training dataset, wherein the training dataset comprises a paired dataset and an un-paired dataset, and wherein the training dataset comprises image data acquired using two or more MR imaging devices; training a deep network model using the training dataset; obtaining an input MR image; and transforming the input MR image to a target image style using the deep network model.