Magnetic Resonance Sequence Optimization for Rapid Substance Detection

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Solution Overview

Problem

Current magnetic resonance fingerprinting methods require lengthy magnetic sequences to detect substances in examination objects, making them inefficient for rapid substance identification.

Innovation Solution

A method that involves a control facility generating a magnetic resonance sequence optimized for specific substances, including varying flip angles and repetition times, to detect substances by capturing signals at specific instants, allowing for faster and more efficient detection without the need for spatially resolved measurements.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If magnetic resonance fingerprinting methods are used to detect substances, then substance detection capability is improved, but measurement time increases significantly

Engineering Contradiction:
Improvesubstance detection capabilityVSAvoidmeasurement time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-calculating and storing signal characteristics for multiple substances under various conditions before the actual measurement. During measurement, the system only needs to compare the measured signal with the pre-stored characteristics, eliminating the need for time-consuming real-time analysis and enabling rapid substance identification

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent implements partial action by measuring only specific signal characteristics that are sufficient for substance identification rather than acquiring complete spatially resolved images. By focusing on essential measurement parameters and ignoring redundant information, the system achieves substance detection with significantly reduced measurement time

Inventive Principle:
Principle #16Partial or excessive action

2Loss of information

If conventional MRT imaging methods are used, then spatial distribution information is obtained, but substance detection efficiency decreases

Engineering Contradiction:
Improvespatial distribution informationVSAvoiddetection efficiency
Core Design Contradiction:
Loss of informationVSProductivity

Solution Approach 1:

The patent extracts and isolates the specific signal characteristics related to substance identification from the complete MRT signal. By separating the relevant substance-specific parameters from the full spatial distribution data, the system achieves rapid substance detection without requiring complete imaging information

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent creates a universal detection framework that can identify multiple different substances using the same measurement and analysis approach. The pre-calculated signal characteristics database enables the system to detect various substances through a single standardized process, improving overall detection efficiency across different substance types

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables quicker detection of substances by optimizing the magnetic resonance sequence for the specific substance, reducing measurement time and improving detection sensitivity, while minimizing unnecessary measurements if the substance is not present.

Implementation Method 1

apparatuses for magnetic resonance tomography (MRT) are imaging apparatuses that use a strong external magnetic field to orient the nuclear spins of an object to be examined and to excite them to precession about the corresponding orientation by applying an RF excitation pulse

Methodology Applied
Scientific EffectMagnetic resonance: Resonance

Implementation Method 2

The precession or the transition of the spins from this excited state into a state with lower energy generates an electromagnetic alternating field as a response, which can be detected as an MR-MRT signal via receiving antennas

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Implementation Method 3

A position encoding can be impressed on the signals with the aid of magnetic gradient fields

Methodology Applied
Scientific EffectMagnetic field gradient: Magnetic Field

Data Source

PatentUS20240122495A1Detecting a Specified Substance in an Examination Object
Publication Date: 2024.04.18 SIEMENS HEALTHINEERS AG
  • US20240122495A1 patent drawing
  • US20240122495A1 patent drawing
  • US20240122495A1 patent drawing

AI summary

Techniques are described for detecting a specified substance in an examination object by way of a magnetic resonance apparatus. A controller ascertains a magnetic resonance sequence comprising at least one sub-sequence for detecting at least one substance to be detected in the examination object as a function of the at least one substance to be detected, and ascertains at least one measuring instant for capturing a respective MRT signal to detect the at least one substance to be detected in the examination object as a function of the at least one substance to be detected. The at least one MRT signal is evaluated for fulfillment of a predetermined detection condition, and a presence of the at least one substance to be detected is established when the at least one MRT signal fulfils the predetermined detection condition.