MRF Out-of-View Artifact Suppression via Adaptive Coil Combination

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Solution Overview

Problem

Conventional magnetic resonance fingerprinting (MRF) techniques lack effective suppression of out-of-view artifacts, which limits the quality of MRF images and subsequent parameter estimates, requiring manual selection of regions-of-interest and assuming equal artifact contribution across parallel receive coils.

Innovation Solution

A method and system for MRF that acquire data using a non-Cartesian, variable density sampling trajectory, generate coil images with a larger field-of-view, determine noise covariance, apply an adaptive coil combination for artifact suppression, and compare the suppressed data with a dictionary to identify tissue properties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional MRF techniques are used without artifact suppression, then the acquisition process is simple and fast, but out-of-view artifacts degrade image quality and parameter estimation accuracy

Engineering Contradiction:
Improveimage qualityVSAvoidprocessing complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The method performs preliminary actions by generating coil images with a larger field of view before the main processing, and calculating noise covariance from out-of-view regions in advance. This preliminary preparation enables the subsequent adaptive coil combination to effectively suppress artifacts while maintaining processing efficiency

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent introduces an adaptive coil combination technique that uses noise covariance information as an intermediary to suppress out-of-view artifacts. The noise covariance calculated from out-of-view regions serves as a mediator to guide the artifact suppression process, improving image quality without requiring complex manual intervention

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If manual selection of region-of-interest is used for artifact suppression, then artifact suppression can be targeted, but the process requires user skill and time

Engineering Contradiction:
Improveparameter estimation accuracyVSAvoidoperational simplicity
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system performs self-service by automatically determining the region-of-interest and calculating noise covariance without requiring manual user input. The adaptive coil combination technique autonomously identifies out-of-view regions and uses them to suppress artifacts, eliminating the need for user skill in region selection while maintaining high parameter estimation accuracy

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The method performs preliminary action by automatically generating coil images with a larger field of view and calculating noise covariance from out-of-view regions before the main processing. This preliminary automated preparation eliminates the need for manual region-of-interest selection by the user

Inventive Principle:
Principle #10Preliminary action

3Productivity

If equal artifact contribution is assumed across parallel receive coils, then the processing is simple, but the artifact suppression is sub-optimal

Engineering Contradiction:
Improveprocessing efficiencyVSAvoidimage quality
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent applies local quality by calculating separate noise covariance information for each coil from out-of-view regions, rather than assuming equal artifact contribution. This localized approach allows each coil to be processed according to its specific noise characteristics, improving image quality while maintaining processing efficiency through automated methods

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The method changes the parameter approach by transitioning from assuming equal artifact contribution across coils to calculating individual noise covariance for each coil. This parameter change enables the adaptive coil combination to optimally suppress artifacts from each coil based on its specific noise characteristics

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS11125847B2System and method for out-of-view artifact suppression for magnetic resonance fingerprinting
Publication Date: 2021.09.21 CASE WESTERN RESERVE UNIV
  • US11125847B2 patent drawing
  • US11125847B2 patent drawing
  • US11125847B2 patent drawing

AI summary

A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report.