MRI-Compatible Ceramic Cannula for Precise Substance Delivery

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current MRI-guided diagnostic and interventional systems face challenges in accurately delivering substances to deep brain locations with minimal trauma and controlling the flow of substances during therapeutic procedures.

Innovation Solution

A cannula system comprising a rigid, MRI-compatible tubular member made of ceramic material with a conformal polymeric sleeve and a transfer tube, designed for precise substance delivery, along with an MRI-guided surgical system that automatically segments MR image data to generate real-time visualizations of the cannula and substance distribution, facilitating accurate placement and flow control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If a rigid tubular member is used for accurate substance delivery, then manufacturing precision is improved, but the device complexity increases due to material selection constraints

Engineering Contradiction:
Improvedelivery accuracyVSAvoidmaterial composition
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The cannula employs a composite structure consisting of a rigid tubular member made from MRI-compatible material (such as ceramic or specialized polymer) combined with a flexible outer sheath. This composite design allows the inner rigid portion to maintain structural integrity and delivery precision while the outer sheath provides flexibility for navigation and MRI compatibility, thus resolving the contradiction between manufacturing precision and device complexity.

Inventive Principle:
Principle #40Composite materials

2Reliability

If MRI-compatible materials are used, then reliability in MRI-guided procedures is improved, but the ease of manufacture deteriorates due to material processing constraints

Engineering Contradiction:
ImproveMRI compatibilityVSAvoidfabrication difficulty
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The cannula is divided into separate segments: an inner rigid tubular member made from MRI-compatible material and an outer flexible sheath. This segmentation allows each component to be manufactured independently using appropriate processes for its specific material requirements, then assembled together. The inner member can be precisely fabricated from MRI-compatible materials like ceramic or specialized polymers, while the outer sheath can be manufactured separately, thereby improving reliability without excessively complicating the overall manufacturing process.

Inventive Principle:
Principle #1Segmentation

3Reliability

If a conformal polymeric sleeve is added, then protection of the tubular member is improved, but the device complexity increases

Engineering Contradiction:
Improvestructural protectionVSAvoidcomponent layers
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The conformal polymeric sleeve is nested over the rigid tubular member, with the inner tubular member positioned within the outer sheath. This nested configuration provides structural protection to the fragile rigid member while maintaining a relatively simple two-layer construction. The protective function is achieved through the outer sheath enveloping the inner member, thus improving reliability without significantly increasing device complexity beyond the essential protective covering.

Inventive Principle:
Principle #7Nested doll (Nesting)

Data Source

PatentUS20240017005A1MRI-compatible surgical cannulae for transferring a substance to and/or from a patient
Publication Date: 2024.01.18 CLEARPOINT NEURO INC
  • US20240017005A1 patent drawing
  • US20240017005A1 patent drawing
  • US20240017005A1 patent drawing

AI summary

A cannula for transferring a substance to and/or from a patient includes a tubular support sleeve and a transfer tube. The support sleeve includes a rigid tubular member defining a lumen extending from a proximal end to a distal end of the tubular member. The transfer tube is positioned in the lumen and extends beyond each of the proximal end and the distal end of the tubular member. The tubular member includes a rigid, MRI-compatible material.