MRI Diffusion Imaging Sequences for Nyquist Artifact Suppression

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Solution Overview

Problem

Conventional magnetic resonance echo plane imaging (EPI) is prone to Nyquist and acceleration artifacts due to factors like eddy currents and gradient coil heating, and existing methods struggle to effectively suppress both types of artifacts simultaneously.

Innovation Solution

A magnetic resonance imaging method involving multiple diffusion-weighted imaging sequences in different directions, each with specific pre-dephasing gradient pulse areas, followed by data fusion processing to acquire and combine k-space data sets, thereby suppressing both Nyquist and acceleration artifacts.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Speed

If conventional echo plane imaging is used to achieve fast imaging, then imaging speed is improved, but Nyquist artifacts and acceleration artifacts appear in the image

Engineering Contradiction:
Improveimaging speedVSAvoidartifacts
Core Design Contradiction:
SpeedVSObject-affected harmful factors

Solution Approach 1:

The patent segments the k-space data acquisition into multiple diffusion directions, acquiring data in different directional planes and then combining them through data fusion processing. This segmentation approach allows the system to maintain fast imaging while reducing artifacts by distributing the acquisition across multiple directional views rather than a single EPI trajectory.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent uses data fusion processing to combine k-space data sets from multiple diffusion directions, creating a composite image that leverages information from all directions. This composite approach suppresses artifacts that appear in individual directional views while maintaining the fast imaging capability of EPI.

Inventive Principle:
Principle #40Composite materials

2Speed

If parallel imaging acceleration is applied to speed up EPI, then imaging speed is improved, but acceleration artifacts appear in edge regions

Engineering Contradiction:
Improveimaging speedVSAvoidacceleration artifacts
Core Design Contradiction:
SpeedVSObject-affected harmful factors

Solution Approach 1:

The patent introduces a new dimension by acquiring data in multiple diffusion directions rather than relying solely on parallel imaging acceleration within a single plane. This dimensional approach to acceleration reduces dependence on aggressive parallel imaging factors that cause edge artifacts while maintaining overall imaging speed.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

3Object-affected harmful factors

If multiple diffusion directions are acquired to improve image quality, then artifact suppression is improved, but scan time increases

Engineering Contradiction:
Improveartifact suppressionVSAvoidscan time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent merges the acquisition of multiple diffusion directions into a single signal acquisition process by applying diffusion-weighted imaging sequences in different directions within the same scan. This combining approach achieves artifact suppression from multiple directions without proportionally increasing total scan time.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent maintains continuous useful action by acquiring diffusion-weighted data in multiple directions during a single uninterrupted signal acquisition. This continuous multi-directional sampling improves artifact suppression while minimizing idle time that would otherwise extend the scan duration.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively suppresses both Nyquist and acceleration artifacts without increasing scan time or requiring additional software, maintaining image quality by adjusting pre-dephasing gradient pulse areas based on diffusion directions and number of acquisitions.

Implementation Method 1

a gradient coil used to generate a gradient pulse

Methodology Applied
Scientific EffectElectromagnetic Induction: Electromagnetic Induction

Implementation Method 2

a radio-frequency coil used to generate a radio-frequency pulse

Methodology Applied
Scientific EffectElectromagnetic Radiation:

Implementation Method 3

magnetic resonance imaging system and method

Methodology Applied
Scientific EffectMagnetic Resonance:

Data Source

PatentUS12566232B2Magnetic resonance imaging system and method
Publication Date: 2026.03.03 GE PRECISION HEALTHCARE LLC
  • US12566232B2 patent drawing
  • US12566232B2 patent drawing
  • US12566232B2 patent drawing

AI summary

A magnetic resonance imaging system and method is provided. The magnetic resonance imaging method comprises: in a single signal acquisition, applying a plurality of diffusion-weighted imaging sequences in a plurality of diffusion directions, respectively, to acquire a plurality of k-space data sets. Each diffusion-weighted imaging sequence comprising a pre-dephasing gradient pulse and a plurality of phase encoding gradient pulses applied after the pre-dephasing gradient pulse, and the pre-dephasing gradient pulses in the plurality of diffusion-weighted imaging sequences, when sorted according to area values, successively having a first standard area difference determined on the basis of the number of the plurality of diffusion directions. The method further includes performing data fusion processing on the plurality of k-space data sets in the single signal acquisition to obtain a magnetic resonance image.