MRI Diffusion Group Cycling to Reduce Gradient Amplifier Stress

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Solution Overview

Problem

Magnetic resonance imaging (MRI) diffusion gradient cycling methods cause significant stress on gradient amplifiers, leading to overheating and prolonged repetition times, which extend the acquisition time of diffusion-weighted imaging volumes, and are incompatible with state-of-the-art motion correction algorithms.

Innovation Solution

Implementing diffusion group cycling by organizing diffusion encoding gradients into N groups, allowing all slices to be acquired back-to-back within An*TR, where N is two or larger, ensuring each gradient is applied at least once per TR, and utilizing algorithms to optimize gradient allocation for load balancing and motion correction.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Temperature

If diffusion gradient cycling is implemented to reduce stress on gradient amplifiers, then overheating and repetition time are improved, but the acquisition time of diffusion-weighted imaging volume is extended

Engineering Contradiction:
Improvegradient amplifier temperatureVSAvoidacquisition time of diffusion-weighted imaging volume
Core Design Contradiction:
TemperatureVSLoss of time

Solution Approach 1:

The patent segments the diffusion gradients into N groups (where N ≥ 2), with each group containing multiple diffusion gradient directions. This segmentation allows the system to cycle through groups of gradients rather than applying all gradients sequentially, reducing the temporal footprint of each volume while distributing the thermal load across multiple TR cycles. The imaging slices are acquired back-to-back for all diffusion gradients corresponding to a group within An*TR time, where An is the number of diffusion gradients in each group.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements periodic cycling through N groups of diffusion gradients, where each group is applied repeatedly across multiple TR cycles. This periodic action pattern (group cycling) allows the system to maintain load balancing and reduce peak thermal stress on gradient amplifiers while completing the full diffusion weighting within a shorter total acquisition time compared to traditional sequential gradient cycling.

Inventive Principle:
Principle #19Periodic action

2Stress or pressure

If diffusion gradient cycling is implemented to manage thermal stress, then gradient amplifier stress is reduced, but motion sensitivity increases

Engineering Contradiction:
Improvegradient amplifier stressVSAvoidmotion sensitivity
Core Design Contradiction:
Stress or pressureVSObject-affected harmful factors

Solution Approach 1:

By segmenting diffusion gradients into N groups and acquiring all slices for a group back-to-back within An*TR, the patent creates discrete temporal blocks that isolate motion artifacts to specific groups rather than spreading them across the entire diffusion scan. This segmentation allows motion correction algorithms to more effectively track and correct motion within each group's acquisition window.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent incorporates feedback mechanisms through its group cycling structure, where the acquisition pattern is designed to be compatible with state-of-the-art motion correction algorithms. The load balancing and temporal distribution of gradients create feedback loops that allow real-time monitoring and adjustment of motion artifacts, improving the robustness of diffusion imaging.

Inventive Principle:
Principle #23Feedback

3Stress or pressure

If traditional diffusion gradient cycling is used, then gradient stress is managed, but compatibility with motion correction algorithms is lost

Engineering Contradiction:
Improvegradient amplifier stressVSAvoidcompatibility with motion correction algorithms
Core Design Contradiction:
Stress or pressureVSAdaptability or versatility

Solution Approach 1:

The patent introduces dynamic adaptability by designing the group cycling structure to accommodate various motion correction algorithms. The flexible grouping of diffusion gradients (where N ≥ 2 and each group has An gradients) allows the system to dynamically adjust acquisition patterns to match the requirements of different motion correction methods, maintaining versatility and adaptability in clinical settings.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces the temporal footprint of each volume, minimizes motion sensitivity, and maintains load balancing, while being compatible with state-of-the-art motion correction algorithms, resulting in more robust and efficient diffusion imaging compatible with multi-center studies.

Implementation Method 1

magnetic field gradients (Gx, Gy, and Gz) are employed

Methodology Applied
Scientific EffectMagnetic field gradients: Magnetic Field

Implementation Method 2

The resulting set of received nuclear magnetic resonance (NMR) signals are digitized and processed

Methodology Applied
Scientific EffectNuclear magnetic resonance:

Implementation Method 3

Long diffusion encoding gradients create significant stress for the semiconductors in the gradient amplifiers. To avoid overheating

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Data Source

PatentUS12429546B2System and method for diffusion group cycling
Publication Date: 2025.09.30 GE PRECISION HEALTHCARE LLC
  • US12429546B2 patent drawing
  • US12429546B2 patent drawing
  • US12429546B2 patent drawing

AI summary

A computer-implemented method and system for performing magnetic resonance diffusion weighted imaging of an object includes generating, via a processor, a diffusion weighted imaging sequence where all diffusion gradients are allocated into N groups such that all imaging slices are acquired for all the diffusion gradients corresponding to a group of the N groups back-to-back in An*TR, wherein N is two or larger, wherein An is a number of diffusion gradients of each group of the N groups and TR is repetition time, and wherein in each TR every diffusion gradient of the group of the N groups is applied at least once. The computer-implemented method and system also includes acquiring, via the processor, imaging slices for multiple groups of the N groups utilizing the diffusion weighted imaging sequence during a scan of the object utilizing a magnetic resonance imaging scanner.