Deep Learning Reconstruction for MRI Diffusion Tensor Imaging

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Solution Overview

Problem

Diffusion tensor imaging (DTI) and fiber tracking methods in magnetic resonance imaging require extensive data acquisition time, limiting their clinical application due to high costs and inefficiencies.

Innovation Solution

A deep learning network is trained using omnidirectionally sampled diffusion weighted images of training samples, allowing for undersampled diffusion weighted images to be used for predicting diffusion tensor images, reducing the need for extensive scanning and improving imaging efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If omnidirectional sampling is used to ensure accurate fiber tracking, then measurement precision is improved, but data acquisition time increases

Engineering Contradiction:
Improvefiber tracking accuracyVSAvoiddata acquisition time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

A deep learning model is pre-trained using omnidirectionally sampled diffusion weighted images to learn the mapping between undersampled and omnidirectional data. During clinical application, the pre-trained model rapidly reconstructs diffusion tensor images from undersampled data, eliminating the need for time-consuming omnidirectional scanning while maintaining tracking accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses undersampled diffusion weighted images as a simplified copy or representation of the full omnidirectional data. The deep learning model learns to map this reduced data copy to the equivalent omnidirectional diffusion tensor information, enabling accurate fiber tracking without acquiring the complete omnidirectional dataset.

Inventive Principle:
Principle #26Copying

2Reliability

If extensive data acquisition is performed to guarantee fiber tracking accuracy, then reliability is improved, but productivity decreases

Engineering Contradiction:
Improvefiber tracking reliabilityVSAvoidimaging efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent replaces the mechanical data acquisition process (extensive scanning) with an information processing approach (deep learning reconstruction). Instead of mechanically acquiring more data through prolonged scanning, the system uses a trained neural network to computationally generate reliable diffusion tensor images from limited undersampled data, significantly improving imaging efficiency while maintaining reliability.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Manufacturing precision

If deep learning network is trained with omnidirectional data, then imaging quality is maintained, but device complexity increases

Engineering Contradiction:
Improveimaging qualityVSAvoidsystem complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The deep learning model acts as an intermediary component between the magnetic resonance scanner and the diffusion tensor imaging reconstruction process. This intermediary learns the complex mapping relationships during training and handles the computational complexity internally, allowing the overall system to maintain high imaging quality while presenting a simpler operational interface that only requires undersampled data acquisition.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS11275141B2Magnetic resonance diffusion tensor imaging method and device, and fiber tracking method and device
Publication Date: 2022.03.15 SIEMENS HEALTHINEERS AG
  • US11275141B2 patent drawing
  • US11275141B2 patent drawing
  • US11275141B2 patent drawing

AI summary

A magnetic resonance diffusion tensor imaging method and corresponding device. The method includes acquiring omnidirectionally sampled diffusion weighted images of a plurality of training samples; performing diffusion tensor model fitting and undersampling for the omnidirectionally sampled diffusion weighted images of each training sample to obtain an omnidirectionally sampled diffusion tensor image and an undersampled diffusion weighted image; training a deep learning network, with the omnidirectionally sampled diffusion tensor images of the plurality of training samples as training targets and the undersampled diffusion weighted images as training data; acquiring undersampled diffusion weighted images of a target object; and inputting the undersampled diffusion weighted images of target objects into the trained deep learning network to obtain the predicted omnidirectionally sampled diffusion tensor images of the target objects. Also, a fiber tracking method and corresponding device.