MRI Fat Suppression Using Frequency-Selective Saturation Pulses

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Solution Overview

Problem

Magnetic resonance imaging (MRI) techniques face challenges in effectively suppressing chemical shift artifacts between water and fat signals, leading to suboptimal image quality due to residual signals and prolonged exposure times in existing fat suppression methods.

Innovation Solution

A method involving a first slice-selective RF pulse with a specific gradient, followed by a second dephasing gradient, and a third RF pulse with altered gradient amplitude and polarity to selectively saturate and separate the signals of water and fat components, allowing for improved data acquisition with reduced unwanted signal contributions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If spectrally selective suppression is used to suppress fat signals, then fat signal suppression is improved, but residual water signal and prolonged exposure time occur

Engineering Contradiction:
Improvefat signal artifactVSAvoidexposure time
Core Design Contradiction:
Object-affected harmful factorsVSLoss of time

Solution Approach 1:

The patent applies preliminary saturation pulses at the fat resonance frequency before the main imaging sequence to pre-suppress the fat signal. This preliminary action eliminates the need for prolonged exposure times during the main sequence while achieving effective fat suppression without residual artifacts.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent modifies the resonance frequency parameter by applying frequency-selective saturation pulses specifically tuned to the fat resonance frequency (approximately 225 Hz offset from water). This parameter change allows selective suppression of fat signals while preserving water signals, resolving the contradiction between fat suppression effectiveness and exposure time.

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If inversion recovery sequences are used for fat suppression, then fat signal suppression is improved, but water signal intensity is reduced and exposure time is prolonged

Engineering Contradiction:
Improvefat signal artifactVSAvoidwater signal intensity
Core Design Contradiction:
Object-affected harmful factorsVSUse of energy by moving object

Solution Approach 1:

The patent applies local quality by using frequency-selective saturation pulses that act only on the fat resonance frequency component while leaving the water resonance frequency component unaffected. This localized frequency-specific action suppresses fat signals without reducing water signal intensity, overcoming the limitation of inversion recovery sequences.

Inventive Principle:
Principle #3Local quality

3Device complexity

If chemical shift artifact is allowed to occur, then image acquisition is simplified, but image quality deteriorates due to signal shifting

Engineering Contradiction:
Improvesequence complexityVSAvoidspatial encoding accuracy
Core Design Contradiction:
Device complexityVSManufacturing precision

Solution Approach 1:

The patent converts the harmful chemical shift effect into a beneficial feature by exploiting the frequency difference between fat and water protons. Instead of trying to eliminate the frequency shift, the method uses frequency-selective saturation pulses tuned to the fat frequency to suppress fat signals while preserving water signals, thereby improving image quality without complicating the sequence.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances image quality by effectively suppressing fat signals while maintaining water signal integrity, reducing exposure time, and allowing for more precise control over slice thickness and position, thereby improving the diagnostic value of MRI data sets.

Implementation Method 1

The resonant frequencies of the examinable nuclei are different. At a magnetic field strength of 1.5 T, protons have a resonant frequency of approximately 63 MHz

Methodology Applied
Scientific EffectLarmor precession: Resonance

Implementation Method 2

A differentiation in the resonant frequencies, particularly in the proton resonant frequencies, is additionally caused by the nuclei being in different chemical environments. This frequency shift is also termed 'chemical shift'.

Methodology Applied
Scientific EffectChemical shift: Resonance

Implementation Method 3

For magnetic resonance examinations, examination objects are placed in a magnetic field in order to produce, in the examination object, a longitudinal magnetization of nuclei spins in the direction of the external magnetic field, which magnetization can be used for magnetic resonance experiments.

Methodology Applied
Scientific EffectMagnetic resonance: Resonance

Implementation Method 4

A gradient is a non-constant magnetic field which is superimposed on the main magnetic field B0. A gradient is used to make the resonant frequency of the protons spatially dependent.

Methodology Applied
Scientific EffectGradient dephasing: Lorentz Force

Data Source

PatentUS10048339B2Method and magnetic resonance scanner for generating a data set
Publication Date: 2018.08.14 SIEMENS HEALTHINEERS AG
  • US10048339B2 patent drawing
  • US10048339B2 patent drawing
  • US10048339B2 patent drawing

AI summary

In a method and a magnetic resonance scanner for generating a data set, a first RF pulse is applied simultaneously with a first gradient having a first amplitude and a first polarity, and at least one second gradient is applied having a second amplitude and a second polarity. A second RF pulse is applied simultaneously with a third gradient having a third amplitude and a third polarity. The third amplitude is different from the first amplitude and/or the third polarity is different from the first polarity. The scan signal generated using the second RF pulse is then read out.