MRI Image Processing Circuits for Real-Time Surgical Visualization

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Solution Overview

Problem

Current Deep Brain Stimulation (DBS) systems face challenges in achieving optimal clinical efficacy due to the imprecision in locating electrodes during surgical procedures, leading to reduced effectiveness in treating conditions like Parkinson's disease, as conventional methods rely heavily on pre-operative imaging and may result in less than optimal outcomes for up to 30% of patients.

Innovation Solution

An MRI-guided surgical system that provides real-time, patient-specific visualizations of anatomical structures and surgical tools, allowing for precise placement of electrodes by segmenting image data and using fiducial markers to guide the trajectory of surgical tools, thereby enhancing the accuracy and reliability of the procedure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If pre-operative MRI and CT images are used for electrode placement, then the surgical procedure can be performed, but the precision of electrode localization is insufficient leading to reduced clinical efficacy

Engineering Contradiction:
Improveelectrode localization precisionVSAvoidclinical efficacy
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system segments MRI image data to generate three-dimensional visualizations of anatomical structures, allowing precise identification of target locations and electrode trajectories. This segmentation enables detailed spatial mapping that improves electrode localization precision beyond conventional pre-operative imaging methods.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system provides real-time visual feedback during the surgical procedure by continuously updating three-dimensional visualizations based on MRI image data. This feedback mechanism allows the surgical team to monitor electrode placement accuracy and make adjustments, ensuring optimal clinical efficacy.

Inventive Principle:
Principle #23Feedback

2Productivity

If conventional DBS implantation methods are used, then the procedure can be completed, but the duration is long and efficacy is reduced for up to 30% of patients

Engineering Contradiction:
Improvesurgical procedure efficiencyVSAvoidclinical outcome reliability
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system performs preliminary three-dimensional visualization and trajectory planning before electrode insertion. By pre-defining the optimal surgical path and target locations using segmented MRI data, the system reduces intraoperative decision-making time and streamlines the implantation process, improving surgical efficiency.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

Real-time visual feedback during the procedure allows for immediate verification of electrode position and trajectory accuracy. This continuous monitoring reduces the need for corrective procedures and ensures reliable clinical outcomes, addressing the 30% failure rate associated with conventional methods.

Inventive Principle:
Principle #23Feedback

3Measurement precision

If real-time visualizations are generated using MRI image data and tool data, then the precision of surgical tool placement is improved, but the system complexity increases

Engineering Contradiction:
Improvesurgical tool placement precisionVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system integrates multiple functions into a unified platform: MRI image acquisition, three-dimensional visualization, surgical tool tracking, and real-time feedback. This multi-functional integration, while increasing capabilities, manages complexity through a cohesive architecture that handles diverse tasks within a single system framework.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system introduces a computational modeling layer that acts as an intermediary between raw MRI data and surgical visualization. This intermediary layer processes and segments image data, generates three-dimensional representations, and correlates tool positions with anatomical structures, managing the complexity of real-time processing through modular computational steps.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS11317982B2Image processing circuits for real-time visualizations using MRI image data and predefined data of surgical tools
Publication Date: 2022.05.03 CLEARPOINT NEURO INC
  • US11317982B2 patent drawing
  • US11317982B2 patent drawing
  • US11317982B2 patent drawing

AI summary

Circuits and computer program products onboard and/or adapted to communicate with an scanner that electronically recognize predefined physical characteristics of the at least one tool to automatically segment image data provided by the scanner whereby the at least one tool constitutes a point of interface with the system. The circuits and computer program products are configured to provide a User Interface that defines workflow progression for an image guided surgical procedure and allows a user to select steps in the workflow, and generate multi-dimensional visualizations using the predefined data of the at least one tool and data from images of the patient in substantially real time during the surgical procedure.