MRI Reconstruction Using Multi-Prior Learning for Undersampled Scans

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Solution Overview

Problem

Existing MRI reconstruction methods face challenges in producing high-quality images from under-sampled data, leading to aliasing artifacts and poor signal-to-noise ratio, particularly at high acceleration rates, due to hardware constraints and noise amplification, and require time-consuming empirical parameter tuning.

Innovation Solution

A consistency-aware multi-prior network that integrates parallel imaging and compressed sensing within a deep learning framework, leveraging image, k-space, and calibration priors through a collaborative learning approach, using neural networks to iteratively enhance and refine MRI reconstructions by exploring data redundancy across adjacent slices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If under-sampled k-space data is used for MRI reconstruction, then scan time is reduced, but image quality deteriorates with aliasing artifacts and poor signal-to-noise ratio

Engineering Contradiction:
Improvescan timeVSAvoidimage quality
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent divides the reconstruction task into two separate neural networks: one operating in image space and another in k-space domain. Each network specializes in handling specific aspects of the reconstruction problem, allowing the system to maintain high image quality from under-sampled data by addressing different spatial and frequency domain characteristics separately.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent performs transformations between image space and k-space domain, operating in both spatial and frequency dimensions. By converting between domains and applying modifications in both spaces, the system recovers lost information from under-sampled data and reduces aliasing artifacts that would otherwise degrade image quality.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Productivity

If high acceleration rates are applied, then scan time is reduced, but noise amplification increases

Engineering Contradiction:
Improvescan timeVSAvoidnoise amplification
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent implements iterative reconstruction where the output of one neural network is fed back as input to the other network. The image-space network and k-space network exchange information through multiple iterations, allowing the system to progressively refine the reconstruction and suppress noise amplification that occurs at high acceleration rates.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent introduces an intermediary frequency fusion operation that combines results from both image-space and k-space processing. This fusion mechanism acts as a mediator that integrates the strengths of both approaches while mitigating their individual weaknesses, particularly in reducing noise amplification during high acceleration reconstruction.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Measurement precision

If empirical parameter tuning is performed, then reconstruction accuracy can be improved, but processing time increases

Engineering Contradiction:
Improvereconstruction accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent employs neural networks that are pre-trained to automatically learn optimal reconstruction parameters and patterns from training data. During actual reconstruction, the networks perform self-service by directly processing the under-sampled data without requiring manual empirical parameter tuning, thus maintaining high reconstruction accuracy while significantly reducing processing time.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The patent transforms the reconstruction problem from requiring manual parameter adjustment to using learned parameters embedded in the neural network weights. By changing from empirical parameter tuning to data-driven parameter learning, the system achieves high reconstruction accuracy automatically without the time cost of iterative manual optimization.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12535547B2System and method for consistency-aware learnable multi-prior reconstruction for magnetic resonance imaging
Publication Date: 2026.01.27 THE CHINESE UNIVERSITY OF HONG KONG
  • US12535547B2 patent drawing
  • US12535547B2 patent drawing
  • US12535547B2 patent drawing

AI summary

Techniques for performing iterative MRI image reconstruction by learning complementary multi-prior knowledge from images, k-space data, and calibration data are disclosed. In one method, k-space data is obtained from an MRI scan. Image-space modifications are performed on the k-space data using a first neural network trained to operate on data in image space. The k-space data is converted from the frequency domain to a spatial domain to produce input image-space data. Using the first neural network, output image-space data is generated, which is then converted from the spatial domain to the frequency domain. K-space modifications are performed on the k-space data using a second neural network trained to operate on data in k-space. ACS are encoded using a third neural network to guide the second neural network in learning consistency-aware k-space correlations. The k-space data is converted from the frequency domain to the spatial domain to obtain a reconstructed image.