MRI Off-Resonance RF Pulse Artifacts

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Solution Overview

Problem

Conventional MRI methods face challenges in obtaining homogeneous images due to the inhomogeneity of the main magnetic field, particularly when using off-resonance RF pulses in combination with spatial pre-saturation RF pulses, leading to artifacts and increased specific absorption rate (SAR) values.

Innovation Solution

Applying a first off-resonance RF pulse followed by a second off-resonance RF pulse with a 180-degree phase difference, accompanied by a plurality of auxiliary gradient magnetic fields to offset the inhomogeneity of the main magnetic field, thereby eliminating undesired signals and artifacts.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If off-resonance RF pulses are used in combination with spatial pre-saturation RF pulses, then fat saturation and magnetization transfer are improved, but artifacts are generated due to main magnetic field inhomogeneity

Engineering Contradiction:
Improvefat saturation effectivenessVSAvoidartifacts from magnetic field inhomogeneity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies preliminary corrective actions by introducing auxiliary gradient magnetic fields before image acquisition to counteract the inhomogeneity effects. The method calculates compensation gradients based on measured field inhomogeneity and applies them in advance to cancel out the harmful phase variations that would otherwise create artifacts during the off-resonance RF pulse application.

Inventive Principle:
Principle #9Preliminary anti-action

Solution Approach 2:

The patent changes the parameters of the gradient magnetic fields by introducing auxiliary gradients with specific amplitudes and timings that are optimized to compensate for field inhomogeneity. The method adjusts gradient waveforms dynamically to match the actual field conditions, transforming the system parameters to achieve homogeneous fat saturation and magnetization transfer effects.

Inventive Principle:
Principle #35Parameter changes

2Manufacturing precision

If additional RF pulses are applied to correct magnetic field inhomogeneity, then image homogeneity is improved, but specific absorption rate (SAR) values increase

Engineering Contradiction:
Improveimage homogeneityVSAvoidspecific absorption rate (SAR)
Core Design Contradiction:
Manufacturing precisionVSUse of energy by moving object

Solution Approach 1:

The patent substitutes the use of additional RF pulses with gradient magnetic field manipulation to achieve the same homogeneity correction goal. Instead of applying more electromagnetic energy through RF pulses, the method uses magnetic field gradients to induce phase corrections, thereby reducing SAR while maintaining image quality.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces gradient magnetic fields as an intermediary mechanism to transfer the correction function from the RF domain to the gradient domain. The auxiliary gradients act as mediators that indirectly correct the inhomogeneity effects without requiring additional RF energy input, thus lowering SAR while achieving the desired homogeneity improvement.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach effectively cancels artifacts generated by magnetic field inhomogeneity, reduces the need for post-processing, and decreases SAR values by using gradient magnetic fields instead of additional RF pulses, resulting in more reliable and homogeneous MRI images.

Implementation Method 1

capable of canceling artifacts generated by being sensitive to the inhomogeneity of a main magnetic field

Methodology Applied
Scientific EffectMagnetic field inhomogeneity: Magnetic Field

Implementation Method 2

applying a plurality of auxiliary gradient magnetic fields offsetting the inhomogeneity of a main magnetic field

Methodology Applied
Scientific EffectLorentz force: Lorentz Force

Implementation Method 3

A unit of a chemical shift is represented by ppm (parts per million) and is measured as a relative numeral value. Since a water molecule has a chemical shift of 4.7ppm and the fat molecule has a chemical shift of 1.2ppm, the water molecule and the fat molecule have a difference of 3.5ppm

Methodology Applied
Scientific EffectChemical shift:

Implementation Method 4

selectively exciting the fat and the water using a frequency selective radio frequency (RF) pulse

Methodology Applied
Scientific EffectResonance: Resonance

Data Source

PatentEP3089663B1Magnetic resonance imaging method for canceling artifacts and undesired signals
Publication Date: 2021.11.17 GACHON UNIV OF IND ACADEMIC COOPERATION FOUND
  • EP3089663B1 patent drawingFigure 1
  • EP3089663B1 patent drawingFigure 2
  • EP3089663B1 patent drawingFigure 3

AI summary

A first off resonance radio frequency (RF) pulse and a second off resonance RF pulse having a phase difference of 180 degrees from the first off resonance RF pulse are applied, one or more auxiliary gradient magnetic fields for offsetting inhomogeneity of a main magnetic field generated by applying the first and second off resonance RF pulses are applied, and magnitudes and signs of the auxiliary gradient magnetic fields are appropriately adjusted. Therefore, artifacts generated due to inhomogeneity of a main magnetic field in an imaging method using an off resonance RF pulse may be removed. When this method is applied to an imaging method using a spatial pre-saturation RF pulse, the phenomenon in which spins excited by the pre-saturation RF pulse are excited again by the off resonance RF pulse to return signals, such that undesired signals overlap and appear in an ultimately-obtained signal, may be removed.