MRI ROI Position Correction for Chemical Shift Alignment
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Solution Overview
Problem
Existing MRI and MRS techniques face challenges in accurately identifying the region of interest (ROI) corresponding to a specific chemical shift, leading to inaccuracies in spectral analysis and disease diagnosis.
Innovation Solution
A data processing apparatus that calculates position correction data based on designated chemical shifts to determine the effective ROI, allowing for real-time adjustment and display of the ROI position, thereby aligning with the chemical shift of interest.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If the region of interest (ROI) is set on a positioning image, then the ROI can be visually selected, but the ROI position does not accurately correspond to the chemical shift of interest due to chemical shift variations
Solution Approach 1:
The patent introduces a chemical shift correction mechanism as an intermediary between the positioning image and the spectral analysis. This correction system calculates position adjustment values based on chemical shift differences and applies them to the ROI coordinates, thereby mediating the discrepancy between visual positioning and actual chemical shift correspondence.
Solution Approach 2:
The patent changes the parameter of ROI position coordinates based on chemical shift values. By calculating correction amounts from the difference between actual chemical shift and reference chemical shift, the system dynamically adjusts the ROI position parameters to maintain accurate correspondence with the target metabolite regardless of chemical shift variations.
2Reliability
If chemical shift variations are not corrected, then the spectral analysis can be performed, but the accuracy of disease diagnosis is reduced due to incorrect ROI positioning
Solution Approach 1:
The patent implements a feedback mechanism where the actual chemical shift values obtained from spectral analysis are used to calculate position corrections. These corrections are then applied to adjust the ROI position, and the process can be iterated or validated against reference values to ensure diagnostic accuracy is maintained.
Solution Approach 2:
The patent performs preliminary calculation of position correction values based on expected chemical shift differences before finalizing the ROI selection for spectral analysis. This preliminary correction ensures that the ROI is pre-positioned accurately according to the target chemical shift, preventing positioning errors from affecting subsequent diagnostic analysis.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate identification of metabolite regions, enhancing the accuracy of disease diagnosis and spectral analysis by aligning ROI positions with chemical shifts.
Implementation Method 1
The deviation of the magnetic resonance frequency of each substance from the magnetic resonance frequency of a specific reference substance (i.e., reference magnetic resonance frequency) is called a chemical shift.
Implementation Method 2
When an object is placed in a strong magnetic field, the directions of the respective nuclear spins of molecules constituting the object are aligned and the nuclear spins precess at the Larmor frequency.
Data Source
AI summary
A data processing apparatus includes processing circuitry configured to: acquire data that are based on a magnetic resonance signal acquired from a specific region of an object, the data being acquired for detecting a chemical shift of substance; and perform relation calculation between a designated chemical shift arbitrarily designated in a predetermined range of the chemical shift and displacement amount of a position of the specific region displaced due to the designated chemical shift, as position correction data.