MRI-Based SAR Determination via Thermal Inversion

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Solution Overview

Problem

Existing methods for determining the specific absorption rate (SAR) of radio frequency (RF) radiation, such as using electric field probes, suffer from translational delays and errors due to point-by-point movement, and temperature-based assessments require prolonged heating to detect changes, which can lead to inaccuracies.

Innovation Solution

A system and method that utilize thermal information, including temperature difference maps from magnetic resonance imaging, to determine SAR through inversion of the bioheat equation, using a finite difference approach and L1 weighted norm minimization, to calculate both local and spatially averaged SAR.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If electric field probes are used to measure SAR point-by-point in a grid-like fashion, then measurement coverage can be achieved, but translational delays and translational errors occur due to mechanical movement

Engineering Contradiction:
ImproveSAR measurement accuracyVSAvoidmeasurement stability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent replaces the mechanical probe movement system with an MRI-based thermal mapping system. Instead of physically moving electric field probes through a grid pattern, the invention uses MRI to capture temperature distributions across the entire phantom volume simultaneously, eliminating mechanical translational delays and errors while maintaining comprehensive measurement coverage

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent transitions from one-dimensional point-by-point probe measurements to three-dimensional volumetric temperature mapping using MRI. This dimensional expansion allows simultaneous capture of temperature data throughout the entire phantom volume, eliminating the need for mechanical translation and providing comprehensive SAR distribution information

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If heating duration is kept low to minimize heat diffusion, then temperature distribution accuracy is improved, but detectable temperature change becomes difficult for low power RF emitting devices

Engineering Contradiction:
Improvetemperature measurement accuracyVSAvoiddetectable temperature change
Core Design Contradiction:
Measurement precisionVSPower

Solution Approach 1:

The patent employs iterative feedback between temperature measurements and SAR calculations. Multiple temperature maps are acquired at different time points, and the SAR distribution is repeatedly calculated and refined based on the observed temperature evolution, allowing accurate SAR determination even when individual temperature changes are small

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent performs preliminary measurement of thermal properties (conductivity, heat capacity, perfusion) before the actual SAR measurement experiment. These pre-measured thermal parameters are then used in the heat diffusion equation to accurately interpret small temperature changes and calculate SAR, enabling detection of temperature changes from low power devices

Inventive Principle:
Principle #10Preliminary action

3Power

If heating duration is prolonged to detect temperature change in low power devices, then detectable temperature change is achieved, but heat diffusion increases causing inaccuracies

Engineering Contradiction:
Improvedetectable temperature changeVSAvoidSAR measurement accuracy
Core Design Contradiction:
PowerVSMeasurement precision

Solution Approach 1:

The patent uses iterative feedback where temperature maps are acquired at multiple time points during heating, and SAR calculations are repeatedly updated based on the observed temperature evolution. This feedback loop allows the system to compensate for heat diffusion effects by comparing temperature changes against the heat diffusion model predictions

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent changes the approach from trying to minimize heating duration to instead measuring thermal properties (conductivity, heat capacity, perfusion) and using these parameters in a heat diffusion model. By incorporating these parameter changes into the calculation framework, the system can accurately determine SAR even when heat diffusion occurs during prolonged heating

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for accurate and efficient calculation of SAR, reducing errors and providing precise measurements of RF radiation absorption, even with short heating durations, by leveraging thermal properties and temperature changes.

Implementation Method 1

temperature difference maps from magnetic resonance imaging

Methodology Applied
Scientific EffectMagnetic resonance: Maser

Implementation Method 2

Exposure to the RF radiation can result in an increased heating of tissue via Joule and Dielectric heating mechanisms

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Implementation Method 3

Exposure to the RF radiation can result in an increased heating of tissue via Joule and Dielectric heating mechanisms

Methodology Applied
Scientific EffectDielectric heating: Dielectric Heating

Data Source

PatentUS10180362B2System, method and computer-accessible medium for determining specific absorption rate obtained based on magnetic resonance imaging and temperature property measurements
Publication Date: 2019.01.15 NEW YORK UNIV
  • US10180362B2 patent drawing
  • US10180362B2 patent drawing
  • US10180362B2 patent drawing

AI summary

Systems, methods and computer-accessible mediums for determining a specific absorption rate (SAR) of a radio frequency (RF) radiation on an object(s) can be provided, which can, for example hardware arrangement configured to receive thermal information for a portion(s) of the at least one object, and determine the SAR based on the thermal information.