3D Anatomical Model Segmentation from 2D MRI Data

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Solution Overview

Problem

The segmentation and visualization of medical image data, particularly MRI images, is a complex task due to noisy data, low contrast, and large variations between patients, requiring advanced data-driven approaches to accurately classify anatomical structures and abnormalities, which existing methods struggle to efficiently accomplish.

Innovation Solution

A computing device system that loads two-dimensional MRI images, creates a three-dimensional anatomical model, segments it into components, adjusts properties to match medical data, and uses machine learning to detect abnormalities, generating automated videos or animations, employing anatomical constraints, user interface tools, and machine learning algorithms for improved accuracy and efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If manual image segmentation is used for CT or MRI scans, then segmentation accuracy can be achieved, but it requires expensive specialized software and many hours of work

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidtime required for segmentation
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary actions by automatically generating an initial 3D anatomical model from 2D MRI images using machine learning algorithms before manual refinement. This pre-segmentation step creates a head start, reducing the time required for manual adjustment while maintaining accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system creates a 3D copy/model of the anatomical structure from 2D image data. This digital twin can be manipulated and refined more efficiently than direct 2D segmentation, allowing faster iteration and adjustment while preserving segmentation accuracy.

Inventive Principle:
Principle #26Copying

2Productivity

If simple threshold value segmentation is used, then processing speed is improved, but it lacks the resolution to tell the differences between soft tissues

Engineering Contradiction:
Improveprocessing speedVSAvoidsoft tissue differentiation resolution
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system changes the parameter space by transitioning from simple intensity thresholding to multi-parameter analysis including texture features, anatomical constraints, and machine learning-based classification. This allows soft tissue differentiation while maintaining computational efficiency through optimized algorithms.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The system replaces the mechanical thresholding approach with an intelligent system combining machine learning models and anatomical knowledge graphs. This substitution enables sophisticated soft tissue characterization without the computational burden of traditional manual segmentation methods.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Measurement precision

If advanced data-driven approaches are used to accurately classify anatomical structures, then segmentation accuracy is improved, but device complexity increases

Engineering Contradiction:
Improveanatomical structure classification accuracyVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system segments the complex task into distinct modules: 2D image preprocessing, 3D model generation, anatomical constraint application, and machine learning classification. Each module handles a specific aspect, reducing overall system complexity while maintaining high classification accuracy through specialized processing at each stage.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system introduces intermediate representations and anatomical knowledge graphs as mediators between raw image data and final classification. These intermediaries structure the data in ways that simplify processing while preserving the information needed for accurate anatomical structure classification.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS11158047B2System and method for segmentation and visualization of medical image data
Publication Date: 2021.10.26 MULTUS MEDICAL LLC
  • US11158047B2 patent drawing
  • US11158047B2 patent drawing
  • US11158047B2 patent drawing

AI summary

A computing device has a processor. A display is coupled to the processor. A user interface is coupled to the processor for entering data into the computing device. A memory is coupled to the processor, the memory storing program instructions that when executed by the processor, causes the processor to: load a plurality of two-dimensional MRI image data, the two-dimensional MRI image data taken along multiple planes to create a stack of two-dimension MRI images; load a three-dimensional anatomical model associated with an anatomical area of the two-dimensional MRI image data; segment the three-dimensional model may into multiple components, at least one of the components being modified to accurately represent the slacked two-dimensional images to form a modified three-dimensional model; and adjust at least one property on the modified three-dimensional model to form a modified anatomical model to match the medical data image.