MRI Shells Trajectory Acquisition for Off-Resonance Blurring
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Solution Overview
Problem
Conventional MRI methods face challenges in reducing scan time while maintaining image quality, particularly due to sensitivity to off-resonance effects and limitations in readout duration, especially when using non-Cartesian trajectories like the shells k-space sampling trajectory.
Innovation Solution
The method involves reducing the repetition time (TR) and readout duration for central shells in the shells sampling pattern, using a variable TR to minimize the impact of off-resonance effects, and employing tilted equatorial shell acquisitions to cover larger spherical shells efficiently, thereby reducing off-resonance blurring and alleviating slew rate restrictions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If the readout duration is extended to acquire sufficient k-space data, then the image quality and spatial resolution are improved, but the off-resonance blurring increases and the temporal resolution deteriorates
Solution Approach 1:
The patent segments the k-space acquisition into multiple interleaved shells, where each shell is acquired during a separate TR period. This segmentation allows the total readout duration to be distributed across multiple shorter acquisitions, reducing off-resonance blurring within each individual readout while still achieving complete k-space coverage through the combination of all shells.
Solution Approach 2:
The patent employs periodic repetition of the shell acquisition sequence across multiple TR periods, with each period acquiring a different interleaved shell. This periodic action enables the system to accumulate sufficient k-space data over time without requiring any single readout to be excessively long, thereby maintaining both image quality and minimizing off-resonance effects.
2Loss of time
If the scan time is reduced by using undersampling, then the temporal resolution is improved, but the image quality deteriorates due to aliasing artifacts
Solution Approach 1:
The patent segments the k-space into multiple spherical shells and acquires them in an interleaved manner across different TR periods. This segmentation allows undersampling within each individual shell acquisition while ensuring that the combined data from all shells provides sufficient sampling density to reconstruct high-quality images without severe aliasing artifacts.
Solution Approach 2:
The patent applies different sampling strategies to different regions of k-space by using variable density within each shell, with higher sampling density near the center of each shell and lower density at the periphery. This local quality approach optimizes the tradeoff between scan time and image quality by concentrating sampling efforts where they are most needed while accepting lower sampling in regions that contribute less to overall image fidelity.
3Area of stationary object
If additional interleaves are used to cover larger spherical shells, then the k-space coverage is improved, but the peripheral nerve stimulation increases
Solution Approach 1:
The patent uses periodic repetition of the shell acquisition sequence across multiple TR periods, with each period acquiring a different interleaved shell. This approach distributes the gradient demands over time, allowing adequate k-space coverage to be achieved without requiring all interleaves to be acquired simultaneously within a single TR, thereby reducing the peak gradient slew rates that cause peripheral nerve stimulation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for shorter TR and readout times, improving spatial resolution and reducing off-resonance artifacts, particularly beneficial in contrast-enhanced MR angiography by allowing more time to acquire high spatial frequency data during peak contrast agent concentration, while avoiding additional interleaves that could cause peripheral nerve stimulation.
Implementation Method 1
the nucleus precesses around this direction at a characteristic angular frequency (Larmor frequency) which is dependent on the strength of the magnetic field and on the properties of the specific nuclear species
Implementation Method 2
If, however, the substance, or tissue, is subjected to a magnetic field (excitation field B1) which is in the x-y plane and which is near the Larmor frequency, the net aligned moment, Mz, may be rotated, or 'tipped', into the x-y plane
Implementation Method 3
This is accomplished by employing magnetic fields (Gx, Gy, and Gz) which have the same direction as the polarizing field B0, but which have a gradient along the respective x, y and z axes
Data Source
AI summary
A method for prescribing a scan on an MRI system includes selecting a general pulse sequence to be used during a time-resolved imaging process of a subject using an MRI system. The method also includes setting a first set of scan parameters to more specifically prescribe the general pulse sequence and setting a second set of scan parameters using a formula that relates time resolution and spatial resolution resulting from the first set of scan parameters. The method then includes performing the time-resolved imaging process using the general pulse sequence, the first set of scan parameters, and the second set of scan parameters.


