MRI Signal Coding for SNR Enhancement via Slice Segmentation

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Solution Overview

Problem

Current MRI technologies face limitations in signal-to-noise ratio (SNR) due to noise in detected signals, which hinders the resolution of fine details and scan speed, especially at higher magnetic field strengths, and are constrained by cost, image uniformity, and radio-frequency energy absorption.

Innovation Solution

The implementation of signal coding, which involves collecting sums of coded signals from all components rather than isolating and processing individual components, to enhance SNR and allow for flexible scan time management, leveraging mechanisms like RF and gradient field modulation to distinguish and decode signals effectively.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If magnetic field strength is increased to improve SNR, then signal-to-noise ratio is improved, but cost of instrumentation and operation increases

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidcost of instrumentation and operation
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The imaging volume is divided into multiple slices that are imaged separately and then combined. This segmentation allows the system to achieve volumetric SNR enhancement without requiring a single high-field strength scanner, thereby reducing instrumentation cost while maintaining measurement precision.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Multiple slice images are merged into a composite volumetric image. By combining signals from multiple slices with appropriate phase cycling and signal addition, the system achieves √N-fold SNR enhancement equivalent to volumetric imaging, reducing the need for higher magnetic field strength equipment.

Inventive Principle:
Principle #5Merging (Combining)

2Measurement precision

If magnetic field strength is increased to improve SNR, then signal-to-noise ratio is improved, but radio-frequency energy absorption or SAR increases

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidradio-frequency energy absorption
Core Design Contradiction:
Measurement precisionVSUse of energy by moving object

Solution Approach 1:

The total imaging task is segmented into multiple slice acquisitions at lower field strength, avoiding the high RF energy absorption associated with high-field volumetric imaging. Each slice is acquired with reduced SAR, and the cumulative effect achieves the desired SNR without excessive energy absorption.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The imaging protocol uses periodic phase cycling across multiple slices with alternating phase encodings. This periodic action allows signal accumulation over time while distributing RF energy exposure, reducing peak SAR compared to continuous high-field volumetric imaging.

Inventive Principle:
Principle #19Periodic action

3Productivity

If conventional multi-slice MRI is used, then scan time is reduced compared to volumetric imaging, but SNR enhancement is limited

Engineering Contradiction:
Improvescan speedVSAvoidSNR enhancement
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

Phase encoding gradients are applied preliminarily in alternating directions across multiple slices before signal acquisition. This preliminary phase modulation enables subsequent signal addition that constructively enhances SNR while maintaining the rapid multi-slice acquisition timeline, achieving both speed and sensitivity.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system uses feedback from previously acquired slice signals to optimize the acquisition of subsequent slices. Phase cycling and signal accumulation strategies are adjusted based on intermediate results, allowing progressive SNR enhancement while maintaining efficient scan timing.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach achieves a √N-fold SNR enhancement and flexible scan time allocation, significantly improving image resolution and speed, particularly in multi-slice MRI protocols, while managing noise and maintaining image quality.

Implementation Method 1

gradient-based signal coding for multi-slice imaging

Methodology Applied
Scientific EffectMagnetic field gradient encoding: Magnetic Field

Implementation Method 2

RF-based signal coding for multi-slice imaging

Methodology Applied
Scientific EffectRadio-frequency pulse modulation: Phase Modulation

Data Source

PatentUS12111376B2Imaging with signal coding and structure modeling
Publication Date: 2024.10.08 ZHU YUDONG
  • US12111376B2 patent drawing
  • US12111376B2 patent drawing
  • US12111376B2 patent drawing

AI summary

A technology is provided for multi-component and/or multi-configuration imaging with coding, signal composition, signal model, structure model, structure model learning, decoding, reconstruction, performance prediction and performance enhancement. A magnetic resonance imaging example comprises acquiring signal samples in accordance with a coding scheme and a k-space sampling scheme, identifying a structure model in a data assembly formed using an extraction operation, and generating a result consistent with both the acquired signal samples and the identified structure model.