Multi-Channel MRI Spectrometer Modules With Synchronization
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Solution Overview
Problem
The high cost and large size of existing MRI systems limit their availability and accessibility for various applications and experiments, making them less feasible for widespread use, especially in educational and research settings.
Innovation Solution
A multi-channel MRI system is developed, incorporating a system-on-chip (SoC) with a field programmable gate array (FPGA) and processor core, which includes scalable transmit and receive channels, synchronization modules, and machine learning capabilities to autonomously configure the system, enabling low-cost, portable, and multi-modal imaging solutions.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional MRI systems are used, then imaging capability is achieved, but cost and size become prohibitively high
Solution Approach 1:
The patent divides the MRI system into multiple independent spectrometer channels, each capable of operating autonomously. Each channel includes its own RF coil, amplifier, and processing unit, allowing the system to be scaled from single-channel to multi-channel configurations. This segmentation enables modular deployment where institutions can start with fewer channels and add more as needed, significantly reducing initial cost and complexity while maintaining full imaging capability.
Solution Approach 2:
The spectrometer channels are designed with universal functionality to perform multiple NMR and MRI experiments. Each channel can independently execute various pulse sequences and spectroscopy protocols, allowing a single multi-channel system to replace multiple specialized instruments. This multi-functionality reduces the need for separate dedicated systems for different applications, thereby lowering overall institutional investment.
2Adaptability or versatility
If multi-channel configuration is implemented, then functionality and versatility are improved, but synchronization complexity increases
Solution Approach 1:
The patent merges the synchronization function into a centralized master clock that distributes timing signals to all spectrometer channels. This unified timing architecture ensures that all channels operate in precise synchrony without requiring complex peer-to-peer synchronization protocols. The master clock approach simplifies the overall system architecture while enabling coordinated multi-channel operation for advanced imaging sequences.
Solution Approach 2:
A dedicated synchronization module acts as an intermediary between the master clock and individual spectrometer channels. This module receives timing signals from the master clock and distributes them to each channel's RF transmitter and receiver, ensuring coherent operation. The intermediary synchronization module isolates channels from direct interference while maintaining precise temporal coordination, reducing cross-channel interference and simplifying individual channel design.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system significantly reduces the cost of MRI consoles, making them more accessible for educational institutions and researchers, allowing for the use of nuclear magnetic resonance (NMR) and MRI systems at a lower cost, similar to 3D printers, and enabling portable MRI systems for point-of-care applications.
Implementation Method 1
The spectrometer is configured to transmit RF signals to excite respective RF coils
Implementation Method 2
to receive MR sensor signals from the excited respective RF coils responsive to excitation thereof
Data Source
AI summary
An example multi-channel magnetic resonance (MR) system is described. The system includes a plurality of radio frequency (RF) coils and a plurality of spectrometer transceiver channels. Each of the channels including a spectrometer coupled a respective set of the RF coils. The spectrometer is configured to transmit RF signals to excite respective RF coils and to receive MR sensor signals from the excited respective RF coils responsive to excitation thereof. The spectrometer is configured to perform MR spectrometry to provide MR measurement data based on the received MR sensor signals for the respective channel. A synchronization module is coupled to the spectrometer of the respective channel. The synchronization module is configured to synchronize the spectrometer of the respective channel with spectrometers in other channels via a communication link.