MRI T1 Imaging Compensation for Incomplete Magnetization

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Solution Overview

Problem

Current MRI technologies face challenges in accurately obtaining T1 distribution images of the heart, which are crucial for identifying myocardial infarction, due to incomplete inversion or saturation of longitudinal magnetization, leading to suboptimal image contrast and diagnostic accuracy.

Innovation Solution

The MRI apparatus employs a processing circuit to compensate for incomplete inversion or saturation by applying inversion recovery or saturation pulses in synchronization with biological signals, such as ECG, and varying the timing of data acquisition to improve the accuracy of T1 distribution image generation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If inversion recovery pulse or saturation pulse is applied to acquire magnetic resonance signal, then T1 distribution image can be obtained for myocardial infarction identification, but incomplete inversion or saturation of longitudinal magnetization occurs leading to reduced image contrast and diagnostic accuracy

Engineering Contradiction:
ImproveT1 distribution image accuracyVSAvoidinversion efficiency
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent applies curve fitting with inversion efficiency compensation where the processing circuit iteratively adjusts the inversion efficiency parameter to match the acquired signal data. The curve fitting process provides feedback on the actual inversion performance, allowing the system to compensate for incomplete inversion and accurately determine T1 values even when inversion efficiency is less than 100%.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent changes the parameter representation by introducing inversion efficiency as a variable parameter in the curve fitting model. Instead of assuming perfect inversion, the system models the actual inversion efficiency as a parameter to be determined, allowing accurate T1 measurement despite imperfect pulse application. This parameter change transforms the problem from one requiring perfect inversion to one that can accommodate realistic pulse imperfections.

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If inversion recovery pulse or saturation pulse is applied to acquire magnetic resonance signal, then T1 distribution image can be obtained for myocardial infarction identification, but incomplete inversion or saturation of longitudinal magnetization occurs leading to suboptimal image contrast

Engineering Contradiction:
Improveimage contrastVSAvoidpulse application accuracy
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The curve fitting process provides feedback on the actual magnetization state after pulse application. By comparing the acquired signal with the modeled recovery curve that includes inversion efficiency as a parameter, the system can determine the actual contrast characteristics and adjust the T1 calculation to reflect the true tissue properties despite imperfect pulse application.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent transforms the image contrast problem by changing from assuming ideal pulse parameters to modeling actual pulse performance parameters. The inversion efficiency parameter captures the real-world deviations in pulse application, allowing the system to calculate accurate T1 values and maintain optimal image contrast for distinguishing infarcted from normal myocardium.

Inventive Principle:
Principle #35Parameter changes

3Ease of manufacture

If curve fitting is performed without inversion efficiency compensation, then processing is simpler, but T1 distribution image accuracy is reduced

Engineering Contradiction:
Improveprocessing complexityVSAvoidT1 value accuracy
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent enhances the curve fitting model by adding inversion efficiency as an additional parameter. This parameter change allows the model to account for imperfect pulse application while maintaining a relatively simple computational approach. The processing circuit performs curve fitting with this additional parameter to accurately determine T1 values without requiring complex alternative processing methods.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the accuracy of T1 distribution imaging by compensating for inefficiencies in pulse applications, allowing for clearer differentiation between normal and infarcted myocardial tissue, thereby improving diagnostic capabilities.

Implementation Method 1

acquire a magnetic resonance signal after applying an inversion recovery pulse or a saturation pulse

Methodology Applied
Scientific EffectInversion recovery:

Implementation Method 2

compensating an incomplete saturation of a longitudinal magnetization resulting from a saturation efficiency of the saturation pulse

Methodology Applied
Scientific EffectSaturation: Magnetic Saturation

Implementation Method 3

a static field magnet, a gradient coil, at least one radio frequency coil and a processing circuit

Methodology Applied
Scientific EffectStatic magnetic field: Magnetic Field

Implementation Method 4

a static field magnet, a gradient coil, at least one radio frequency coil and a processing circuit

Methodology Applied
Scientific EffectGradient magnetic field: Magnetic Field

Implementation Method 5

magnetically excites nuclear spins of an object set in a static magnetic field with RF (radio frequency) signals having the Larmor frequency and reconstructs images based on MR (magnetic resonance) signals generated due to the excitation

Methodology Applied
Scientific EffectLarmor precession:

Implementation Method 6

processing for compensating an incomplete inversion of a longitudinal magnetization resulting from an inversion efficiency of the inversion recovery pulse

Methodology Applied
Scientific EffectInversion efficiency compensation:

Implementation Method 7

processing for compensating an incomplete saturation of a longitudinal magnetization resulting from a saturation efficiency of the saturation pulse

Methodology Applied
Scientific EffectSaturation efficiency compensation:

Data Source

PatentUS10359490B2Magnetic resonance imaging apparatus and magnetic resonance imaging method with curve fitting expression providing compensation for inversion recovery, or with curve fitting expression providing compensation for saturation
Publication Date: 2019.07.23 TOSHIBA MEDICAL SYST CORP
  • US10359490B2 patent drawing
  • US10359490B2 patent drawing
  • US10359490B2 patent drawing

AI summary

According to one embodiment, a magnetic resonance imaging apparatus includes a data acquiring part and a processing circuit. The data acquiring part is configured to acquire a magnetic resonance signal after applying an inversion recovery pulse or a saturation pulse. The processing circuit generates magnetic resonance examination data based on the magnetic resonance signal, by data processing including processing for compensating an incomplete inversion of a longitudinal magnetization resulting from an inversion efficiency of the inversion recovery pulse or processing for compensating an incomplete saturation of a longitudinal magnetization resulting from a saturation efficiency of the saturation pulse.