MRI Water-Fat Separation Using Machine Learning Classification

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Solution Overview

Problem

Current water-fat image separation techniques in MRI are prone to errors due to static magnetic field inhomogeneities, leading to increased scanning and processing times without significantly improving image quality or reliability.

Innovation Solution

A method using machine learning algorithms to classify signal components from water and fat tissues, allowing for separate acquisition and output of diagnostic nuclear magnetic resonance images, which reduces errors caused by magnetic field inhomogeneities and optimizes image processing without lengthening scanning or processing times.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If Dixon methods are used for water-fat image separation, then water and fat images can be separated, but scanning time and processing time increase significantly

Engineering Contradiction:
Improvewater-fat image separation reliabilityVSAvoidscanning time and processing time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent changes the fundamental parameter for separation from chemical shift-based phase information to machine learning classification using intensity parameters. This allows separation to be achieved with standard single-echo acquisitions rather than requiring multiple echoes at different TE values, thus reducing scanning time while maintaining separation reliability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the traditional Dixon method's reliance on phase information and chemical shift with a machine learning-based intensity classification system. This substitution eliminates the need for complex multi-echo acquisitions and unwrapping algorithms, significantly reducing both scanning time and processing requirements while maintaining accurate water-fat separation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If traditional Dixon methods are used, then water-fat separation is achieved, but image quality deteriorates due to B0 inhomogeneity errors

Engineering Contradiction:
Improvewater-fat separation accuracyVSAvoidimage quality
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent replaces the Dixon method's phase-based separation mechanism with a machine learning intensity-based classification system. This substitution makes the separation process immune to B0 inhomogeneity effects that plague traditional Dixon methods, as the classification is based on intensity patterns rather than phase information that is sensitive to magnetic field variations.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The machine learning algorithm automatically learns and adapts to the specific imaging conditions and tissue characteristics from the acquired intensity images, eliminating the need for manual intervention or complex post-processing to correct B0 inhomogeneity artifacts. The system self-corrects for field inhomogeneities through its training on diverse imaging data.

Inventive Principle:
Principle #25Self-service

3Reliability

If fat signal suppression is used, then pathology visualization is improved, but fat-related pathologies cannot be detected

Engineering Contradiction:
Improvepathology detection capabilityVSAvoiddetection of fat-related pathologies
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent segments the MRI signal into distinct water and fat components using machine learning classification, allowing independent analysis of each component. This segmentation enables the simultaneous detection of both water-related pathologies (where fat suppression would be beneficial) and fat-related pathologies (where fat signal preservation is necessary), providing comprehensive diagnostic capability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent creates a universal imaging approach that can serve multiple diagnostic purposes: water-only images for detecting water-related pathologies, fat-only images for detecting fat-related pathologies, and the ability to suppress fat signals when needed for specific diagnostic questions. This multi-functionality allows a single imaging protocol to address diverse diagnostic requirements without requiring separate specialized sequences.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively separates water and fat images, improving reliability and reducing processing time while maintaining image quality, by using machine learning to classify signal components and optimize image acquisition sequences.

Implementation Method 1

diagnostic applications of magnetic resonance imaging (MRI) detect the signal of protons

Methodology Applied
Scientific EffectMagnetic resonance:

Implementation Method 2

methods known as Dixon methods rely on phase shifts created by differences in the resonance frequency of fat and water

Methodology Applied
Scientific EffectChemical shift:

Data Source

PatentUS11971466B2System and method for fat and water diagnostic imaging
Publication Date: 2024.04.30 ESAOTE
  • US11971466B2 patent drawing
  • US11971466B2 patent drawing
  • US11971466B2 patent drawing

AI summary

A method for separately acquiring and outputting diagnostic nuclear magnetic resonance images based on water and fat derived signals, which method provides that the separation of the signal components corresponding to the intensity of the resulting pixels or voxels derived from the water of tissues in the body under examination from those signal components derived from the fat tissues in said body under examination of the step is performed by means of a machine learning algorithm, or with automatic learning and which algorithms are configured to classify the signal component as derived from water or fat tissues in the body under examination.