MTA Bone Graft Composition for Porosity and Particle Strength

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Solution Overview

Problem

Conventional synthetic bone grafting materials face challenges with poor handleability, low particle strength, and varying porosity affecting bone regeneration, making it difficult to form a stable structure during surgical procedures.

Innovation Solution

A bone grafting material composition is developed by mixing mineral trioxide aggregates (MTA) with a porous synthetic bone grafting material, comprising tricalcium silicate and/or dicalcium silicate, and hydroxyapatite or beta-tricalcium phosphate, to enhance strength and handleability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If the porosity of synthetic bone grafting material is increased to promote revascularization and healing, then the surface area increases to facilitate reabsorption, but the particle strength decreases making it difficult to maintain volume under external pressure

Engineering Contradiction:
ImproveporosityVSAvoidparticle strength
Core Design Contradiction:
Stability of the object's compositionVSStrength

Solution Approach 1:

The patent combines porous synthetic bone grafting material particles with mineral trioxide aggregates (MTA) to create a composite material. The MTA acts as a binding agent that fills the spaces between particles and binds them together, providing structural support and maintaining volume under pressure while preserving the high porosity needed for revascularization and bone regeneration.

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If conventional synthetic bone grafting material is used in powder form, then it can be easily prepared and applied, but the handleability is poor and significant time is required to form the approximate shape of alveolar bone

Engineering Contradiction:
Improvepreparation easeVSAvoidhandleability
Core Design Contradiction:
Ease of manufactureVSEase of operation

Solution Approach 1:

The patent changes the physical state parameter of the bone grafting material from dry powder to a paste form by mixing with liquid. This parameter change significantly improves handleability and ease of operation, allowing the material to be easily placed and shaped in the alveolar bone defect without requiring extensive manipulation time.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If conventional synthetic bone grafting material is used, then bone regeneration can occur, but blood permeability is poor making it difficult for proteins in plasma to be adsorbed

Engineering Contradiction:
Improvebone regeneration capabilityVSAvoidblood permeability
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent utilizes porous synthetic bone grafting material particles that provide high porosity and surface area. This porous structure enhances blood permeability and allows proteins in plasma to be adsorbed effectively, while still maintaining the capability to support bone regeneration through the controlled porosity structure.

Inventive Principle:
Principle #31Porous materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition forms a high-strength structure that maintains shape and volume under pressure, improving surgical ease and bone regeneration outcomes.

Implementation Method 1

The composition forms a high-strength structure that maintains shape and volume under pressure

Methodology Applied
Scientific EffectChemical Bonding: Chemical Bonding

Implementation Method 2

Conventional synthetic bone grafting materials have poor blood permeability, making it difficult for proteins in plasma to be adsorbed

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP4725513A1Bone graft composition and manufacturing method thereof
Publication Date: 2026.04.15 MEDIVALUE CO LTD
  • EP4725513A1 patent drawingFigure 1~2
  • EP4725513A1 patent drawingFigure 3~4
  • EP4725513A1 patent drawingFigure 5~7

AI summary

The present invention relates to a bone graft composition comprising mineral trioxide aggregates (MTA) and a porous synthetic bone graft material. The bone graft composition of the present invention can improve the operability of the bone graft composition and form a high-strength structure by adding MTA.