Multi-Active Personal Care System for Cytokine Downregulation
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Solution Overview
Problem
Current skin care compositions fail to effectively reduce skin irritation to the level provided by clobetasol derivatives, despite numerous attempts to incorporate anti-aging and anti-inflammatory ingredients.
Innovation Solution
A personal care composition containing a multi-active system comprising camellia sinensis extract, panthenol, and glycyrrhizinate salt, applied topically to form a treated surface, which downregulates cytokines and reduces skin irritation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If corticosteroid components such as clobetasol derivatives are used, then anti-inflammatory performance is improved, but product execution versatility deteriorates
Solution Approach 1:
The patent combines three different anti-inflammatory ingredients (corticosteroid component, camellia sinensis extract, and allantoin) into a single multi-active system. This merging allows the composition to achieve the high anti-inflammatory performance of corticosteroids while adding the skin-conditioning benefits of the natural ingredients, thereby maintaining effectiveness across different product types and applications.
Solution Approach 2:
The multi-active system is designed to perform multiple functions simultaneously: providing potent anti-inflammatory action like corticosteroids, adding moisturizing and skin-conditioning benefits from camellia sinensis extract and allantoin, and enabling use in various product formats. This multi-functionality resolves the contradiction by making the composition adaptable to different product executions while maintaining reliable anti-inflammatory performance.
2Object-affected harmful factors
If multiple anti-inflammatory ingredients are incorporated, then skin irritation reduction is improved, but composition complexity increases
Solution Approach 1:
The patent merges three anti-inflammatory ingredients into a coordinated multi-active system where each component contributes to overall irritation reduction. The corticosteroid provides potent anti-inflammatory action, camellia sinensis extract adds antioxidant and soothing effects, and allantoin contributes moisturizing and skin-healing properties. This combination improves skin irritation reduction while managing complexity through synergistic formulation.
Solution Approach 2:
The composition uses a composite approach by combining ingredients from different chemical classes (corticosteroid, plant extract, and purine derivative) into a unified anti-inflammatory system. This composite material strategy allows the formulation to achieve enhanced irritation reduction performance while the ingredients work together in a coordinated manner, managing the complexity through complementary rather than competing mechanisms.
Data Source
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AI summary
A personal care composition comprising a multi-active system for down regulating cytokines comprising at least three actives, an extract of camellia sinesis, panthenol, and a glycyrrhizinate salt.