Multi-atlas Segmentation Using Landmark-Based Subset Selection

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Solution Overview

Problem

Current multi-atlas segmentation methods for medical images require extensive processing time and computational resources, especially when a large number of anatomical variations are involved, making them impractical for real-time applications.

Innovation Solution

A medical image processing apparatus that selects a subset of atlases based on anatomical landmarks using a distance metric and clustering methods, performing a less computationally intensive initial registration followed by a more accurate non-rigid registration for improved segmentation efficiency.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a large number of atlases are used to improve segmentation accuracy by covering more anatomical variations, then segmentation accuracy is improved, but processing time and computational resources become prohibitively long and intensive

Engineering Contradiction:
Improvesegmentation accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent segments the large set of atlases into subsets based on anatomical similarity. Instead of processing all atlases uniformly, the system divides them into groups and selects representative subsets, reducing the computational burden while maintaining segmentation accuracy across different anatomical variations.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies partial action by selecting only a subset of atlases that are most relevant to the specific image being segmented. Rather than using all available atlases (excessive action), the system identifies and uses only the necessary portion that provides sufficient anatomical coverage for accurate segmentation.

Inventive Principle:
Principle #16Partial or excessive action

2Manufacturing precision

If multiple registration methods are performed on all atlases to improve segmentation quality, then segmentation quality is improved, but computational complexity and processing time increase significantly

Engineering Contradiction:
Improvesegmentation qualityVSAvoidcomputational complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies local quality by performing different registration methods on different subsets of atlases rather than applying the same comprehensive registration to all atlases. The system performs initial registration on all atlases, then applies more computationally intensive refined registration only to selected subsets, optimizing computational resources while maintaining segmentation quality.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent performs preliminary registration of all atlases to a reference atlas before selecting subsets for refined registration. This preliminary action establishes initial alignment and enables subsequent selective processing, reducing overall computational complexity while maintaining segmentation quality.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If comprehensive registration of all atlases is performed to ensure accurate anatomical alignment, then anatomical alignment accuracy is improved, but processing efficiency deteriorates

Engineering Contradiction:
Improveanatomical alignment accuracyVSAvoidprocessing efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent segments the atlas population into subsets based on anatomical similarity metrics. By dividing the comprehensive registration task into smaller subset-specific registrations, the system maintains anatomical alignment accuracy for each subset while improving overall processing efficiency through parallel and selective processing.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent changes the parameter of atlas selection by using anatomical similarity metrics to identify and select subsets of atlases that are most relevant to the target image. This parameter change enables the system to maintain high anatomical alignment accuracy by selecting appropriate atlases while improving processing efficiency by excluding irrelevant ones.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS9818200B2Apparatus and method for multi-atlas based segmentation of medical image data
Publication Date: 2017.11.14 TOSHIBA MEDICAL SYST CORP
  • US9818200B2 patent drawing
  • US9818200B2 patent drawing
  • US9818200B2 patent drawing

AI summary

An image data processing apparatus including a data receiver receiving image data to be segmented, and an atlas selection processor accessing a plurality of atlas data sets and selecting a subset of the atlas data sets for use in segmenting the image data, wherein the atlas selection processor is configured to select the subset of atlas data sets in dependence on the positions of one or more anatomical landmarks comprised in the plurality of atlas data sets.