Multi-axis Charged Particle Beam Control for Tumor Irradiation

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Solution Overview

Problem

Current particle beam therapy for cancer treatment lacks precise control over charged particle beam dimensions, leading to challenges in timely, accurate, and precise tumor irradiation.

Innovation Solution

A multi-axis controlled charged particle irradiation beam system that independently controls horizontal, vertical, energy, and intensity of the charged particle beam, coordinated with patient respiration and positioning, allowing for multi-axis and multi-field irradiation to achieve precise dosages and minimize damage to healthy tissue.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If traditional particle beam therapy is used without multi-axis control, then the treatment system is simpler, but the precision and accuracy of tumor irradiation deteriorates

Engineering Contradiction:
Improveprecision of tumor irradiationVSAvoidcomplexity of beam control system
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The beam control system is segmented into independent control axes (horizontal position, vertical position, energy, intensity) that can be adjusted separately. This segmentation allows precise control of each parameter to achieve accurate tumor irradiation while maintaining manageable system complexity through modular independent controls.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces multi-axis control dimensions beyond traditional single-axis beam control. By adding horizontal and vertical position control, energy modulation, and intensity control as separate dimensions, the system achieves precise three-dimensional tumor irradiation accuracy while organizing complexity through structured dimensional separation.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Measurement precision

If charged particle beam dimensions are not precisely controlled, then the system operation is simpler, but the accuracy of tumor irradiation deteriorates

Engineering Contradiction:
Improveaccuracy of tumor irradiationVSAvoidease of beam control operation
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system incorporates feedback mechanisms that monitor beam position and dimensions in real-time, automatically adjusting the control parameters to maintain precise tumor irradiation accuracy. This feedback operation simplifies the operator's task by handling precision adjustments automatically while maintaining high measurement precision.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system enables precise control by allowing independent changes to multiple parameters (position, energy, intensity) rather than requiring complex coordinated adjustments. This parameter separation makes operation easier while maintaining accuracy, as each parameter can be optimized independently for the specific treatment requirement.

Inventive Principle:
Principle #35Parameter changes

3Manufacturing precision

If multi-axis control is implemented, then the precision of beam delivery improves, but the device complexity increases

Engineering Contradiction:
Improveprecision of beam deliveryVSAvoidcomplexity of control system
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The control system is divided into separate control modules for each axis (horizontal, vertical, energy, intensity), allowing precision beam delivery through independent parameter adjustment. This segmentation manages device complexity by organizing controls into discrete, manageable modules rather than a single complex control unit.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system implements dynamic control capabilities that allow real-time adjustment of beam parameters during treatment. This dynamic operation enables high precision beam delivery adapted to patient movement and treatment requirements, while the dynamic nature is managed through programmed control sequences that organize complexity in time-based manner.

Inventive Principle:
Principle #15Dynamics

4Productivity

If independent control of beam parameters is added, then the accuracy and timeliness of treatment improves, but the system complexity increases

Engineering Contradiction:
Improveefficiency of treatment deliveryVSAvoidcomplexity of beam control
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system performs preliminary calculations and setup of beam parameters based on treatment planning before actual delivery. This preliminary action organizes the complexity by pre-computing optimal parameter sequences, allowing efficient real-time execution while reducing on-the-fly computational complexity and improving treatment delivery efficiency.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The multi-axis control system is designed to handle multiple treatment scenarios and patient positions through a universal control framework. This multi-functionality improves productivity by adapting to various treatment requirements without requiring separate specialized systems, while managing complexity through a unified control architecture that handles diverse cases through parameter variation rather than structural variation.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables precise and accurate irradiation of tumors with controlled energy distribution, reducing harm to surrounding tissues and improving treatment efficiency by coordinating beam control with patient movement and positioning.

Implementation Method 1

These particles damage the DNA of cells, ultimately causing their death. Cancerous cells, because of their high rate of division and their reduced ability to repair damaged DNA, are particularly vulnerable to attack on their DNA.

Methodology Applied
Scientific EffectIonizing radiation: Ionisation

Implementation Method 2

Proton therapy systems typically include: a beam generator, an accelerator, and a beam transport system to move the resulting accelerated protons to a plurality of treatment rooms

Methodology Applied
Scientific EffectElectromagnetic acceleration: Electromagnetic Induction

Implementation Method 3

Proton therapy systems typically include: a beam generator, an accelerator, and a beam transport system to move the resulting accelerated protons

Methodology Applied
Scientific EffectLorentz force: Lorentz Force

Data Source

PatentUS8901509B2Multi-axis charged particle cancer therapy method and apparatus
Publication Date: 2014.12.02 BALAKIN ANDREY VLADIMIROVICH
  • US8901509B2 patent drawing
  • US8901509B2 patent drawing
  • US8901509B2 patent drawing

AI summary

The invention comprises a multi-axis charged particle irradiation method and apparatus. The multi-axis controls includes separate or independent control of one or more of horizontal position, vertical position, energy control, and intensity control of the charged particle irradiation beam. Optionally, the charged particle beam is additionally controlled in terms of timing. Timing is coordinated with patient respiration and/or patient rotational positioning. Combined, the system allows multi-axis and multi-field charged particle irradiation of tumors yielding precise and accurate irradiation dosages to a tumor with distribution of harmful proximal distal energy about the tumor.