Multi-cellular closure device for tissue opening reduction
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Solution Overview
Problem
Conventional treatments for Patent Foramen Ovale (PFO) and other internal tissue defects often require invasive surgery, which poses risks and is less efficient compared to less invasive methods.
Innovation Solution
A medical system comprising a closure device and delivery device that can selectively position and deploy a multi-cellular body with anchors to approximate tissue in internal tissue openings, allowing for the reduction of opening size without plastic deformation, and includes features for tissue growth promotion and precise positioning.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If invasive surgery is used to close internal tissue openings, then the closure can be achieved, but the procedure poses risks and has lower efficiency compared to less invasive methods
Solution Approach 1:
The patent introduces a closure device as an intermediary element that is delivered through a catheter to the internal tissue opening. This mediator device performs the closure function without requiring direct surgical intervention, thereby achieving reliable closure while avoiding the risks associated with invasive surgery.
Solution Approach 2:
The patent replaces the mechanical surgical system (knives, forceps, direct manipulation) with a minimally invasive delivery system that uses a catheter-based approach. The closure device is deployed through the catheter using controlled mechanical expansion, substituting complex surgical mechanics with a simpler, more controlled deployment mechanism.
2Productivity
If a closure device is deployed to reduce opening size, then the opening can be closed, but the device must accommodate various sizes and shapes of openings
Solution Approach 1:
The closure device is divided into multiple segments or cells that can independently expand and conform to the specific geometry of the internal tissue opening. This segmentation allows the device to adapt to various sizes and shapes while maintaining efficient closure through the coordinated expansion of individual segments.
Solution Approach 2:
The closure device transitions from a compressed delivery state to an expanded deployed state, dynamically adapting its configuration to match the target opening. This dynamic transformation enables the device to efficiently close openings of varying sizes and shapes through controlled mechanical expansion.
3Length of moving object
If the closure device is made to collapse into a narrow non-deployed orientation, then it can be delivered through the catheter, but it must expand without plastic deformation or failure
Solution Approach 1:
The closure device utilizes flexible cellular structures that can be compressed into a narrow profile for delivery while maintaining structural integrity. The thin-walled cellular design allows significant compression for catheter delivery, then expands reliably without plastic deformation due to the elastic properties of the cellular structure.
Solution Approach 2:
The device undergoes controlled parameter changes during deployment, transitioning from a compressed state with small dimensions to an expanded state with larger dimensions. The material and structural design ensure this parameter change occurs elastically without permanent deformation or structural failure.
Data Source
AI summary
A medical system for treating an internal tissue opening can include a closure device and associated delivery device. The closure device can include a multi-cellular body portion operatively associated with a first anchor and a second anchor. The closure device can be configured to apply lateral force to tissue of the internal tissue opening for tissue approximation. The closure device can also include an ingrowth material. The delivery device can include an actuating assembly configured to partially deploy the closure device by a first movement, and deploy a second portion of the closure device by a second movement. The delivery device can also include a release assembly to selectively release or disconnect the closure device from the delivery device.