Multi-dose fluid path sterility via segmentation

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Solution Overview

Problem

Conventional medical connectors and fluid path elements face challenges in maintaining sterility during use, as they can become contaminated upon removal from pre-sterilized packages and during connection processes, especially in non-sterile environments, posing risks to multi-patient systems.

Innovation Solution

A multi-dose disposable system featuring a multi-use fluid path set and a series of single-use fluid path sets, with a foldable casing and a manifold with check valves, ensures sterility by maintaining a sterile fluid path from fluid containers to the patient, allowing for sequential use and minimizing exposure to non-sterile surfaces.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If conventional medical connectors are removed from pre-sterilized packages for use, then they can be connected and used in medical procedures, but they become contaminated by airborne particles and non-sterile surfaces

Engineering Contradiction:
ImproveconnectabilityVSAvoidcontamination
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The fluid path system is divided into multiple segments: a multi-use fluid path set that remains connected to the injector, and multiple single-use fluid path sets that are sequentially connected and disconnected. Each single-use set is sterile when removed from packaging, used for one patient, then discarded, preventing cross-contamination while maintaining ease of operation

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system employs disposable single-use fluid path sets that are discarded after one use. These inexpensive, single-use components eliminate the need to sterilize connectors between patients, as each new patient receives a fresh, sterile fluid path set, solving the contamination problem while maintaining operational simplicity

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Productivity

If a single fluid path set is reused across multiple patients, then resource utilization improves, but sterility cannot be maintained between patients

Engineering Contradiction:
Improveresource utilizationVSAvoidsterility
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The fluid path system is segmented into a reusable multi-use portion and disposable single-use portions. The multi-use fluid path set remains connected to the injector and is reused across multiple patients, while the single-use fluid path sets are discarded after each patient, maintaining sterility without sacrificing resource utilization of the expensive injector components

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The single-use fluid path sets act as intermediaries between the multi-use fluid path set and the patient. These disposable intermediaries transfer the fluid while maintaining sterility, allowing the multi-use portion to be reused without direct contact with multiple patients, thus preserving both sterility and resource utilization

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If connections are made in non-sterile environments, then operational flexibility improves, but sterility of the fluid path is compromised

Engineering Contradiction:
Improveenvironmental flexibilityVSAvoidairborne contaminants
Core Design Contradiction:
Adaptability or versatilityVSObject-affected harmful factors

Solution Approach 1:

The single-use fluid path sets are pre-sterilized and packaged in sterile containers before use. The sterile packaging maintains sterility during transport and storage, and the connection process is designed to maintain sterility until the moment of use, allowing connections to be made in non-sterile environments while preserving sterility of the fluid path

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The disposable single-use fluid path sets eliminate the need for sterile environments during connection, as each set is sterile when removed from packaging and discarded after one use. This allows operational flexibility in non-sterile environments while maintaining sterility through the use of fresh, sealed, single-use components for each patient

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentEP3107614B1Multi-dose fluid delivery system
Publication Date: 2021.08.04 BAYER HEALTHCARE LLC
  • EP3107614B1 patent drawingFigure 1
  • EP3107614B1 patent drawingFigure 2
  • EP3107614B1 patent drawingFigure 3

AI summary

A multi-dose disposable fluid delivery system includes at least one fluid container, a multi-use fluid path set, and a plurality of single-use fluid path sets. The at least one fluid container has a connection port configured for fluidly connecting with a first end of the multi-use fluid path set. The second end of the multi-fluid path set is configured for fluidly connecting to a fluid injection apparatus. The plurality of single-use fluid path sets is connected in sequence to define a fluid path extending from a first single-use fluid path set to a last single- use fluid path set. Each of the plurality single-use fluid path sets has a first end and a second end. The first end of the first single-use fluid path set is configured for connecting to a delivery line. The second end of the last single-use fluid path set is configured for connecting to the injection apparatus.