Multi-Dose Syringe Ring Mechanism for Repeatable Dose Setting

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Solution Overview

Problem

Existing dosing syringes require time-consuming and error-prone manual dose setting, which can be compromised by animal movement, leading to inaccurate dosing, especially when administering consistent doses to multiple animals.

Innovation Solution

A multi-dose syringe with a flanged dose-setting sleeve and rotatable dose-setting ring, featuring a helical indentation on the plunger, allows for precise and repeatable dose setting through interference coupling, preventing accidental changes and ensuring consistent dosing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If a liquid product for injection is prepared in advance and stored, then treatment time is reduced, but bacterial contamination may occur and product stability deteriorates

Engineering Contradiction:
Improvetreatment timeVSAvoidproduct stability
Core Design Contradiction:
Loss of timeVSReliability

Solution Approach 1:

The syringe is divided into separate compartments: a first compartment for the liquid product and a second compartment for the plunger. This segmentation allows the product to be prepared in advance and stored in the first compartment without immediate contact with the plunger, reducing treatment time while maintaining product stability through physical separation that prevents contamination.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A breakable seal acts as an intermediary barrier between the liquid product and the external environment. This seal maintains product stability during storage by preventing bacterial contamination, and can be broken when needed to allow product delivery, thus resolving the contradiction between advance preparation and product stability.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If a solid product is suspended in liquid before administration, then dosing flexibility is improved, but product stability and bacterial contamination risk increase

Engineering Contradiction:
Improvedosing flexibilityVSAvoidproduct stability
Core Design Contradiction:
Adaptability or versatilityVSReliability

Solution Approach 1:

The syringe separates the solid product and liquid suspending agent into different compartments. The solid product can be loaded into the first compartment in advance, and the liquid suspending agent is introduced later by replacing the plunger. This provides dosing flexibility while maintaining product stability through temporal separation of components.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The solid product is prepared and loaded into the syringe in advance, but the suspending action is delayed until the liquid is introduced. This preliminary preparation of the solid product combined with delayed suspension maintains stability while enabling flexible dosing when needed.

Inventive Principle:
Principle #10Preliminary action

3Quantity of substance

If a large volume of liquid product is administered, then single-dose syringes require larger dimensions, but device complexity and handling difficulty increase

Engineering Contradiction:
Improveproduct volumeVSAvoidsyringe dimensions
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The syringe allows continuous administration of large volumes of liquid product through a single device without requiring multiple syringes or complex switching mechanisms. The first compartment is designed to accommodate large volumes, and the continuous plunger mechanism enables uninterrupted delivery, maintaining simplicity while handling large quantities.

Inventive Principle:
Principle #20Continuity of useful action

Data Source

PatentEP4447856B1Multi-dose syringe and method of multiple dosing a liquid or semiliquid product
Publication Date: 2026.05.06 PLATINUM PHARMA SERVICE SRLS
  • EP4447856B1 patent drawingFigure 1
  • EP4447856B1 patent drawingFigure 2
  • EP4447856B1 patent drawingFigure 3

AI summary

The present invention relates to a multi-dose syringe (100) and a method of multiple dosing a product. The syringe (100) comprises a hollow cylindrical body (10) configured to contain a product to be administered in a dosed manner and from which a spout (13) extends which is provided with a product outlet opening (14), and a plunger (20), sliding within the hollow cylindrical body (10). A helical indentation (27) is formed on an outer surface (25) of the plunger (20), which comprises a plurality of teeth (28), each having a first (28a) and a second longitudinal surface (28b) and a first (28c) and a second (28d) transverse surface extending, parallel to each other, orthogonally from a respective longitudinal surface (28a, 28b) and further comprising a flanged dose-setting sleeve (30), irremovably mounted on one end (11) of the hollow cylindrical body (10) for the entry of the plunger (20), and a dose-setting ring (40) mounted on the flanged dose-setting sleeve (30) and rotatable with respect thereto and with respect to the plunger. On facing surfaces (34a, 43a) of the flanged sleeve (30) and of the ring (40) a series of seats (36) and at least one tooth (42) configured to be housed with interference in a respective seat (36) are obtained, respectively, and the plunger (20) is rotatable with respect to the hollow cylindrical body (10) until the first longitudinal surface (28a) of a tooth (28) abuts against a surface (45a) of the ring (40), projecting towards the inside of the hollow cylindrical body (10), so as to set a predetermined dose of the product to be administered.