Multi-Electrode Implantable Device for Deep Brain Stimulation
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Solution Overview
Problem
Current deep brain stimulation (DBS) electrodes lack variability in stimulating brain volumes, making it difficult to target areas outside their cylindrical stimulation zone, and increasing signal amplitude risks tissue damage.
Innovation Solution
An implantable multi-electrode device with a plurality of leads radiating from an assembly block, allowing for precise distribution within a three-dimensional space, along with a biodegradable encapsulant to protect the device during implantation and reduce tissue damage.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Volume of stationary object
If the amplitude of the electrical signal is increased to reach targeted areas outside the cylindrical stimulation zone, then the stimulation volume is increased, but tissue damage adjacent the lead occurs
Solution Approach 1:
The patent divides a single electrode into multiple segmented electrodes arranged in a three-dimensional configuration. Each segment can be independently controlled to deliver electrical stimulation to specific targeted areas within the brain, allowing precise stimulation without requiring high amplitudes that would damage tissue. The segmentation enables the stimulation field to be distributed across multiple smaller targets rather than concentrating energy in one location.
Solution Approach 2:
The patent transitions from a traditional single-point electrode to a multi-electrode array distributed in three-dimensional space. This dimensional expansion allows the device to target multiple locations simultaneously and creates a more flexible stimulation geometry that can reach areas outside the conventional cylindrical zone without increasing signal amplitude, thereby avoiding tissue damage.
2Adaptability or versatility
If traditional single-electrode DBS is used, then the device structure is simple, but the variability in stimulating brain volumes is limited
Solution Approach 1:
The electrode is divided into multiple independent segments that can be individually activated or deactivated. This segmentation provides programmable flexibility in defining stimulation volumes and shapes, allowing the device to adapt to different clinical requirements while maintaining a relatively simple physical structure that can be implanted through standard procedures.
Solution Approach 2:
The multi-electrode array is designed to perform multiple functions: it can stimulate different brain regions, create various stimulation volume shapes, and target areas at different distances from the implant site. This universal capability replaces what would traditionally require multiple different electrode designs or implantation approaches, consolidating versatility into a single device platform.
3Manufacturing precision
If electrodes are distributed in three-dimensional space, then precise stimulation of targeted areas is achieved, but the device structure becomes more complex
Solution Approach 1:
The patent employs a nested structure where multiple electrode segments are integrated within a compact assembly that can be delivered through a single implantation site. The electrodes are arranged in a folded or nested configuration that minimizes the implant footprint while maintaining their three-dimensional spatial distribution, allowing precise targeting without proportionally increasing overall device complexity.
Solution Approach 2:
The electrode segments are arranged in a curved or spherical geometry rather than linear configurations. This curved arrangement allows the electrodes to occupy three-dimensional space efficiently within a compact volume, enabling precise spatial distribution of stimulation points while keeping the overall device structure manageable and suitable for implantation.
Data Source
AI summary
The invention provides an implantable multi-electrode device (300) and related methods and apparatuses. In one embodiment, the invention includes an implantable device (300) comprising: an assembly block (320); and a plurality of leads (340 . . . 348) radiating from the assembly block (320), each of the plurality of leads (340 . . . 348) containing at least one electrode (342A), such that the electrodes are distributed within a three-dimensional space, wherein the assembly block (320) includes a barb (350) for anchoring the assembly block (320) within implanted tissue.


