Multi-Energy X-Ray Imaging for Precise Radiation Target Tracking

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Solution Overview

Problem

Existing image-guided radiation therapy (IGRT) systems using single-energy x-ray images struggle with limited differentiation between soft tissue and radio-opaque objects due to x-ray attenuation characteristics being dependent on energy, leading to suboptimal image quality and target tracking.

Innovation Solution

Generating multi-energy x-ray images using a combination of low and high x-ray energy levels to enhance discrimination between soft tissue and radio-opaque objects, employing apparatus and methods that include dual-energy x-ray sources and detectors, and processing techniques to generate high-definition images for improved target tracking and positioning.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If single-energy x-ray imaging is used in IGRT systems, then the system complexity is reduced and ease of operation is improved, but image quality and differentiation ability between soft tissue and radio-opaque objects deteriorates

Engineering Contradiction:
Improveease of operationVSAvoidimage quality
Core Design Contradiction:
Ease of operationVSMeasurement precision

Solution Approach 1:

The imaging system is segmented into multiple energy channels, with at least a first energy level for soft tissue imaging and a second energy level for bone imaging. This segmentation allows each energy level to be optimized for specific tissue types, improving overall image quality and differentiation ability while maintaining manageable system complexity through modular architecture

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system changes the energy parameter of x-rays by operating at multiple discrete energy levels. This parameter change enables differential attenuation of various tissues, allowing clear differentiation between soft tissue and radio-opaque objects. The controller selectively activates different energy levels based on imaging requirements, resolving the contradiction between operational simplicity and image quality

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If multiple x-ray energy levels are used to improve soft tissue and bone differentiation, then image quality and material discrimination are enhanced, but device complexity increases

Engineering Contradiction:
Improvematerial discriminationVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The x-ray source is designed with multi-functionality to operate at multiple energy levels, serving both soft tissue imaging and bone imaging needs. This universal design eliminates the requirement for separate imaging systems for different tissue types, enhancing material discrimination while controlling device complexity through a single integrated source

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system merges soft tissue imaging and bone imaging capabilities into a single IGRT system by combining multiple energy level operations. The controller integrates the operation of different energy levels and the processing of corresponding images, achieving comprehensive tissue differentiation without requiring multiple separate devices

Inventive Principle:
Principle #5Merging (Combining)

3Speed

If single-energy x-ray images are used, then the imaging system is simpler and faster to operate, but target tracking precision and positioning accuracy deteriorate

Engineering Contradiction:
Improveimaging speedVSAvoidtarget tracking precision
Core Design Contradiction:
SpeedVSMeasurement precision

Solution Approach 1:

The system performs preliminary action by acquiring images at multiple energy levels rapidly and sequentially. The controller coordinates the switching between energy levels and the acquisition of corresponding images, enabling fast capture of both soft tissue and bone structures before treatment delivery, thus maintaining imaging speed while improving target tracking precision through enhanced image quality

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enhances image quality by providing clear differentiation between soft tissue and radio-opaque objects, enabling precise target tracking and positioning during radiation therapy, thereby improving the accuracy and effectiveness of treatment delivery.

Implementation Method 1

a first x-ray source (206) paired with a first x-ray detector (210) and configured to emit imaging radiation (606) at a first energy level

Methodology Applied
Scientific EffectX-ray emission: X-Ray

Implementation Method 2

x-ray attenuation characteristics are dependent on x-ray energy and thus a single energy x-ray image may have limited differentiation ability for certain materials

Methodology Applied
Scientific EffectX-ray attenuation: Absorption (EM radiation)

Data Source

PatentUS12350517B2Image-guided radiation treatment with imaging data using imaging radiation at different energy levels
Publication Date: 2025.07.08 ACCURAY LLC
  • US12350517B2 patent drawing
  • US12350517B2 patent drawing
  • US12350517B2 patent drawing

AI summary

A method of image-guided radiation treatment is described. The method includes processing a first and second sets of image data to generate an enhanced image, wherein the enhanced image comprises a combination of the first and second sets of image data, wherein part or all of the image data comprises a target of a patient. The method also includes registering the enhanced image with another image to obtain a registration result and tracking the target using the registration result to generate tracking information. The method also includes directing treatment delivery to the target based on the tracking information obtained from the enhanced image.