Multi-field Charged Particle Therapy Dose Distribution
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Solution Overview
Problem
There is a need for efficient, even, accurate, and precise delivery of Bragg profile energy to tumors in charged particle cancer therapy, while minimizing radiation dosage to surrounding tissue, and controlling the charged particle cancer therapy system in terms of patient position and timing.
Innovation Solution
A method and apparatus for efficient radiation dosage delivery using a multi-field charged particle cancer therapy system timed with patient respiration, combining charged particle beam injection, acceleration, extraction, and targeting methods, with a negative ion beam source, synchrotron, and X-ray system for precise control of proton beam energy, intensity, and positioning.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If charged particle beam therapy is used to deliver radiation to tumors, then tumor treatment effectiveness is improved, but radiation damage to surrounding tissue increases
Solution Approach 1:
The patent segments the radiation delivery process into multiple fields applied from different directions (anterior, posterior, lateral fields) to systematically cover the tumor volume while controlling exposure to surrounding tissues through coordinated multi-field irradiation
Solution Approach 2:
The system applies different radiation field configurations to different regions of the tumor based on its three-dimensional structure and location, using imaging data to customize the irradiation pattern for each specific tumor site and patient anatomy
2Manufacturing precision
If multi-field irradiation is applied to improve dose distribution, then treatment uniformity is improved, but system complexity increases
Solution Approach 1:
The radiation delivery system is designed to generate and coordinate multiple radiation fields from different directions using a single integrated apparatus, allowing the same system to handle various tumor locations and configurations without requiring separate specialized equipment for each field type
Solution Approach 2:
The system incorporates imaging systems and control mechanisms that provide real-time feedback on tumor position and radiation delivery, automatically adjusting field parameters to maintain uniform dose distribution while managing system complexity through automated coordination
3Measurement precision
If precise control of patient position and beam timing is implemented, then treatment accuracy is improved, but operational complexity increases
Solution Approach 1:
The system performs preliminary imaging and positioning assessments before treatment to establish reference frames and planned field configurations, reducing the complexity of real-time operational adjustments by pre-planning the coordination of multiple radiation fields with patient anatomy
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables precise and efficient delivery of radiation to tumors with minimal damage to surrounding tissue by coordinating proton beam delivery with patient respiration and using advanced beam control systems, ensuring optimal therapeutic outcomes.
Implementation Method 1
a synchrotron to accelerate the charged particles
Implementation Method 2
These particles damage the DNA of cells, ultimately causing their death
Implementation Method 3
Due to their relatively enormous size, protons scatter less easily than X-rays or gamma rays in the tissue
Implementation Method 4
All protons of a given energy have a certain range, defined by the Bragg peak, and the dosage delivery to tissue ratio is maximum over just the last few millimeters of the particle's range
Implementation Method 5
multi-field charged particle cancer therapy system timed with patient respiration
Data Source
AI summary
The invention relates generally to treatment of solid cancers. More particularly, a method and apparatus for efficient radiation dose delivery to a tumor is described. Preferably, radiation is delivered through an entry point into the tumor and Bragg peak energy is targeted to a distal or far side of the tumor from an ingress point. Delivering Bragg peak energy to the distal side of the tumor from the ingress point is repeated from multiple rotational directions. Beam intensity is proportional to radiation dose delivery efficiency. The multi-field irradiation process with energy levels targeting the far side of the tumor from each irradiation direction provides even and efficient charged particle radiation dose delivery to the tumor. Preferably, the charged particle therapy is timed to patient respiration via control of charged particle beam injection, acceleration, extraction, and/or targeting methods and apparatus.