Multi-Head Bioink Spray With Independent Gas-Flow Control

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Solution Overview

Problem

Existing spray devices for delivering bioinks in clinical settings are limited and lack simplicity and ease of use, hindering their widespread adoption in treating tissue injuries.

Innovation Solution

A system comprising at least two spray heads, housing nozzles, a gas inlet, and a control system with valves that allows independent and sequential/simultaneous delivery of bioink components, enabling precise control and flexibility in bioink application.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If traditional spray devices are used for delivering bioinks, then the delivery process becomes complex and difficult to operate, but the system structure remains simple

Engineering Contradiction:
Improveease of useVSAvoidsystem complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The spray device is divided into multiple independent spray heads, each capable of delivering different bioink components. This segmentation allows each head to be optimized for specific functions while maintaining overall system simplicity through modular design

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The spray device integrates multiple functions into a single system: it can deliver different bioink components simultaneously or sequentially, control spray patterns, and accommodate various nozzle types. This multi-functionality eliminates the need for multiple separate devices, improving ease of operation without proportionally increasing complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Adaptability or versatility

If multiple spray heads are integrated into a single system, then the flexibility and precision of bioink delivery improve, but the device complexity increases

Engineering Contradiction:
Improvetreatment methodology flexibilityVSAvoidsystem structure
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system comprises multiple spray heads that can be independently controlled, allowing different treatment methodologies to be applied to different regions of the same wound bed. Each spray head can be activated or deactivated independently, providing versatility without requiring a completely different device for each treatment approach

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The spray heads are integrated into a common housing structure that provides shared support, control mechanisms, and bioink reservoirs. This nested arrangement allows multiple functional units to operate within a compact, unified system, increasing adaptability while minimizing the space and structural complexity required

Inventive Principle:
Principle #7Nested doll (Nesting)

3Productivity

If housing nozzles with larger diameter are used, then the gas flow and spray distribution improve, but the nozzle size increases

Engineering Contradiction:
Improvespray delivery efficiencyVSAvoidnozzle diameter
Core Design Contradiction:
ProductivityVSLength of moving object

Solution Approach 1:

The housing nozzles are positioned around the spray head nozzles in a radial arrangement, distributing gas flow from multiple directions rather than from a single point. This spatial arrangement improves spray distribution and gas-bioink mixing efficiency without requiring any single nozzle to have an excessively large diameter

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Facilitates a simpler and more efficient method for clinicians to apply bioinks, accommodating various treatment methodologies and enhancing the effectiveness of bioink delivery for tissue regeneration.

Implementation Method 1

a gas inlet (30) connected to the housing (20) configured to receive a gas (300)... each housing nozzle (22a, 22b) disposed around the spray head nozzle (125a, 125b)... enabling precise control and flexibility in bioink application

Methodology Applied
Scientific EffectGas flow propulsion: Jet

Implementation Method 2

a control system (40) comprising at least two valves (42a, 42b), each valve (42a, 42b) associated to a housing nozzle (22a, 22b) and configured to control the flow of the gas (300) through each housing nozzle (22a, 22b)

Methodology Applied
Scientific EffectFlow control: Valve

Data Source

PatentEP4631552A1System for providing a bioink in the form of a spray
Publication Date: 2025.10.15 UNIV DE GRANADA
  • EP4631552A1 patent drawingFigure 1~2
  • EP4631552A1 patent drawingFigure 3~4
  • EP4631552A1 patent drawingFigure 5~6

AI summary

The present invention relates to a system for providing a bioink in the form of a spray. The system comprises: a) at least two spray configured to receive at least two syringes comprising a nozzle each, each syringe configured to receive one or more components of the bioink; b) a housing, configured to comprise the at least two spray heads and comprising at least two housing nozzles, the housing nozzle comprising a diameter bigger than the diameter of the spray head nozzle; c) a gas inlet connected to the housing configured to receive a gas; and d) a control system comprising at least two valves, each valve associated to a housing nozzle and configured to control the flow of the gas through each housing nozzle. Each valve is further configured to control the provision of the one or more components of the bioink from each syringe, by controlling the flow of gas through its housing nozzle.