Multi-Immunoassay Analyzer With Unified ELISA, CLIA, and Image Detection
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Solution Overview
Problem
Existing immunometric test apparatuses are limited to a single type of test, such as ELISA, and are either too complex or not user-friendly, lacking versatility and ease of use.
Innovation Solution
An integrated apparatus that can perform multiple immunometric tests automatically, including ELISA, CLIA, and macroarray, using a single-use test device with a control unit that processes signals and images from optical and image detectors, and features a dual rotor system for sample and reagent handling.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If an apparatus is designed to perform multiple types of immunometric tests (ELISA, CLIA, macroarray), then the versatility and adaptability of the apparatus is improved, but the device complexity increases
Solution Approach 1:
The apparatus integrates multiple test execution units (ELISA reader, CLIA reader, macroarray reader) within a single device, allowing it to perform different types of immunometric tests using a unified platform. The housing element can accommodate various test devices, and the control unit manages different detection methodologies, enabling one apparatus to replace multiple specialized devices.
Solution Approach 2:
The apparatus is divided into functionally independent test execution units, each capable of performing specific test types (ELISA, CLIA, macroarray). This modular segmentation allows the system to handle different test protocols separately while maintaining overall integration, reducing the complexity burden by organizing functionality into distinct manageable modules.
2Productivity
If the apparatus integrates multiple test execution units for simultaneous operation, then the productivity is improved, but the device complexity increases
Solution Approach 1:
Multiple test execution units are merged into a single integrated apparatus with shared components including the housing element for test devices, common control unit, and unified signal processing system. This merging enables simultaneous operation of different test types while avoiding the complexity of completely separate standalone systems.
3Ease of operation
If the apparatus uses ready-to-use single determination test devices, then the ease of operation is improved, but the device complexity for handling multiple test device types increases
Solution Approach 1:
The housing element is designed to universally accommodate different types of single-use test devices (ELISA, CLIA, macroarray) through a standardized interface. This universal design allows users to operate different test types without learning multiple complex procedures, as the apparatus handles device-specific complexities internally while presenting a unified user interface.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The apparatus enables simultaneous execution of various immunometric tests with ease and flexibility, supporting different test types without requiring machine changes, ensuring efficient and versatile operation.
Implementation Method 1
at least one optical detector configured to acquire signals and being in operative communication with the control unit which is configured to process said signals for the execution of tests of the Enzyme-Linked Immunosorbent Assay (ELISA) type
Implementation Method 2
at least one optical detector configured to acquire signals and being in operative communication with the control unit which is configured to process said signals for the execution of tests of the Chemiluminescent Immunoassay (CLIA) type
Implementation Method 3
at least one image detector for acquiring images of the test device (containing the sample transferred thereinto), said image detector being in communication with the control unit, which is configured to process said images
Data Source
AI summary
An apparatus for performing immunometric tests is disclosed. The apparatus has a housing element configured to house a plurality of single sample test devices and includes housings for a solid phase, a sample to be analyzed, and reagents, means for acting on the housing element to allow the execution of the desired immunometric test, and a control unit for managing the apparatus. The apparatus includes means for the automatic execution of different immunometric tests, including a detector for executing Enzyme-Linked Immunosorbent Assay (ELISA) tests, a detector for executing Chemiluminescent Immunoassay (CLIA) tests; and an image detector in communication with the control unit for acquiring and processing images of the sample.