Multi-layer Strip for Selective Biological Material Analysis

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Solution Overview

Problem

Conventional biological material measurement devices are limited in their ability to selectively analyze specific materials, such as glucose, in biological samples, resulting in limited effectiveness and application range.

Innovation Solution

A multi-layer strip system comprising a stack of strips with flow channels and reaction units, where reaction-inducing material layers are immobilized to react with biological materials, enabling optical and electrochemical measurement and quantitative analysis of various materials in biological samples.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If conventional biological material measurement devices are used, then the device structure is simple, but the device cannot selectively analyze specific materials contained in biological material samples

Engineering Contradiction:
Improveselective analysis capabilityVSAvoiddevice structure
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The measurement device is divided into multiple independent strips stacked together, where each strip contains a flow channel and a reaction unit with specific reaction-inducing material layers. This segmentation allows each strip to target specific materials (e.g., glucose, cholesterol, hemoglobin) while maintaining overall device simplicity through modular stacking.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The multi-layer strip structure integrates multiple functions into a single device: optical measurement, electrochemical measurement, and quantitative analysis of various biological materials. The stack of strips with different reaction-inducing materials enables the device to universally detect multiple substances simultaneously without requiring separate devices for each analysis.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Productivity

If conventional measurement devices are used, then the device is simple to operate, but the effectiveness and range of application are limited

Engineering Contradiction:
Improvemeasurement effectivenessVSAvoidoperational simplicity
Core Design Contradiction:
ProductivityVSEase of operation

Solution Approach 1:

The device processes multiple biological materials simultaneously through stacked strips, each designed for specific measurements. This segmentation increases productivity by enabling parallel measurement of glucose, cholesterol, hemoglobin, and other materials in a single operational cycle, rather than requiring sequential testing.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The reaction units are pre-loaded with specific reaction-inducing material layers that automatically react with target materials when biological samples are introduced. The optical and electrochemical measurement systems automatically detect and quantify the reactions, reducing the need for complex manual operations while maintaining high measurement effectiveness.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If a stack of multiple strips with reaction-inducing material layers is used, then selective and quantitative analysis of multiple components is enabled, but the device complexity increases

Engineering Contradiction:
Improvequantitative analysis capabilityVSAvoidmulti-layer strip structure
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The quantitative analysis capability is achieved through segmented strips, where each strip contains specialized reaction-inducing material layers for detecting specific materials. The segmentation allows precise measurement of each component independently while maintaining overall device manageability through modular stacking.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The device transitions from single-layer to multi-layer strip stacking, adding a vertical dimension to the measurement system. This dimensional change enables simultaneous quantitative analysis of multiple biological materials by stacking strips with different reaction-inducing materials, increasing measurement precision without significantly complicating the operational interface.

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The multi-layer strip system allows for the selective and quantitative analysis of multiple components in biological materials, enhancing the measurement capabilities beyond conventional devices by enabling optical and electrochemical analysis of specific materials like glucose, cholesterol, and hemoglobin.

Implementation Method 1

a plurality of reaction-inducing material layers which are respectively immobilized in the reaction units of the strips and react with the biological material

Methodology Applied
Scientific EffectChemical reaction: Chemical Bonding

Implementation Method 2

an optical processing module which optically measures the degree of reaction of the biological material with the reaction-inducing material layers

Methodology Applied
Scientific EffectOptical measurement: Absorption Spectroscopy

Implementation Method 3

each strip having a flow channel through which the biological material is injected into the multi-layer strip and a reaction unit which reacts with the biological material, and the reaction-inducing material layers being immobilized in the reaction units of the strips and reacting with specific materials contained in the biological material

Methodology Applied
Scientific EffectElectrochemical measurement: Electrochemiluminescence

Data Source

PatentUS8043489B2Multi-layer strip for use in measuring biological material and system for measuring biological material
Publication Date: 2011.10.25 LG ELECTRONICS INC
  • US8043489B2 patent drawing
  • US8043489B2 patent drawing
  • US8043489B2 patent drawing

AI summary

The multi-layer strip for use in measuring biological material and the system for measuring a biological material are provided, wherein the multi-layer strip includes a stack of a plurality of strips, each having a flow channel and a reaction unit, and the strips may react with specific materials contained in a biological material injected into the multi-layer strip. Thus, it is possible to quantitatively analyze various materials contained in a biological material and to optically and electrochemically measure and quantitatively analyze various materials in a biological material.