Multi-Matrix Monolithic Moulded Part for Active Ingredient Diffusion
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Solution Overview
Problem
Existing diffusion devices with multiple active ingredients face challenges in controlling the release kinetics of each ingredient, leading to uneven diffusion rates and inefficiencies, particularly in antiparasitic treatments where simultaneous or staggered release is necessary for effective pest control or skin protection.
Innovation Solution
A monolithic molded part composed of multiple cohesive thermoplastic polymer matrices, welded together via multi-shot molding, allows each matrix to release its active ingredients at its own rate, ensuring simultaneous or staggered release as needed, achieved by using polymers from the same or different families with compatible solvents, ensuring structural continuity and solvent migration between matrices.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If multiple active ingredients are incorporated into a single polymer matrix carrier, then the device can provide simultaneous diffusion of multiple ingredients, but the release kinetics of each ingredient cannot be controlled independently, leading to uneven diffusion rates
Solution Approach 1:
The single polymer matrix is divided into multiple separate polymer matrices, each containing a different active ingredient. This segmentation allows independent control of release kinetics for each ingredient while maintaining simultaneous diffusion capability. Each matrix acts as an independent diffusion unit with tailored release properties.
Solution Approach 2:
The invention uses a composite structure of multiple polymer matrices with different compositions and properties. Each polymer matrix is selected to provide specific release characteristics for its associated active ingredient, creating a composite system that achieves both simultaneous diffusion and independent kinetic control.
2Quantity of substance
If two different active ingredients are incorporated into a single matrix, then the device can deliver both ingredients, but one ingredient may be easily released while the other is firmly sequestered, leading to uneven release patterns
Solution Approach 1:
Separates the single matrix into multiple distinct polymer matrices, each dedicated to a specific active ingredient. This prevents the competitive interaction that occurs in single matrices, where one ingredient dominates release while another remains sequestered. Each matrix provides stable, controlled release of its assigned ingredient.
Solution Approach 2:
Each polymer matrix is designed with local quality tailored to its specific active ingredient, including appropriate polymer composition, crosslinking density, and porosity. This ensures that each region of the device optimizes release for its specific ingredient, achieving uniform release across all ingredients.
3Device complexity
If a single carrier is used for multiple active ingredients, then the device structure is simple, but the diffusion rates of different ingredients cannot be optimized for their specific therapeutic requirements
Solution Approach 1:
Divides the carrier into multiple polymer matrices that can be arranged in a structured configuration. While the internal structure is more complex than a single matrix, the segmentation enables independent optimization of diffusion rates for each active ingredient while maintaining an integrated device structure.
Solution Approach 2:
The multi-matrix carrier system provides universal functionality by accommodating different active ingredients with different release requirements within a single integrated device. Each matrix performs the universal function of controlled release but with ingredient-specific parameters, achieving both simplicity and optimization.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables controlled and efficient release of active ingredients, optimizing the synergistic or complementary effects for extended efficacy in pest control and skin protection, reducing waste and environmental impact by ensuring full utilization of active materials.
Implementation Method 1
the nature of the macromolecular matrices and/or that of the solvent significantly influence the kinetics of diffusion of the active ingredients incorporated into these carriers
Implementation Method 2
the nature of the macromolecular matrices and/or that of the solvent significantly influence the kinetics of diffusion of the active ingredients
Data Source
AI summary
This invention relates to a monolithic molded part comprising multiple cohesive matrices for the simultaneous diffusion of volatile active ingredients, in contact or separately, wherein said multiple matrix is formed by the combination of several simple matrices, characterized in that each of said simple matrices is capable of containing one or more active ingredient(s), each active ingredient having its own release kinetics.