Multi-Mode Analyte Detection Device Using Integrated Electrodes
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Solution Overview
Problem
Current analyte detection devices lack the ability to combine multiple measurement techniques effectively, resulting in suboptimal accuracy and speed in detecting analytes in biological samples.
Innovation Solution
A device that integrates a first and second electrode with a selector circuit, an electronic signal-conditioning module, an analog-to-digital converter, and a computing unit, allowing for the selection and combination of electrochemical, field-effect, and electro-optical measurement techniques to enhance detection accuracy.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a single measurement technique is used for analyte detection, then the device complexity is reduced, but the measurement precision and detection accuracy are insufficient
Solution Approach 1:
The patent combines multiple measurement techniques (electrochemical, field-effect, and electro-optical) into a single integrated device. The device includes multiple electrodes that can function in different measurement modes, allowing simultaneous or sequential application of different techniques to detect analytes, thereby improving measurement precision while managing device complexity through integration.
Solution Approach 2:
The device is designed with multi-functional electrodes that can serve multiple purposes. The first and second electrodes can operate in electrochemical mode, field-effect mode, or electro-optical mode depending on the measurement requirements. This universality allows a single device to perform multiple measurement techniques, improving analyte detection accuracy without requiring separate dedicated devices for each technique.
2Measurement precision
If multiple measurement techniques are integrated into a single device, then the measurement precision is improved, but the device complexity increases
Solution Approach 1:
The patent introduces a selector circuit as an intermediary component that manages the complexity of multiple measurement techniques. The selector circuit receives control signals and selectively connects the appropriate electrodes to the signal-conditioning module based on the desired measurement mode. This intermediary structure allows the device to integrate multiple techniques while presenting a simplified interface and control mechanism to the user.
3Adaptability or versatility
If multiple electrodes are used for different measurement techniques, then the versatility of the device is improved, but the ease of operation becomes more difficult
Solution Approach 1:
The device incorporates a control system that receives control signals and uses them to selectively activate appropriate measurement techniques through the selector circuit. The system can process control signals from various sources (manual input, automated sequences, or external devices) and automatically configure the electrodes and signal-conditioning module accordingly, reducing the operational burden on the user while maintaining high versatility.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device achieves more precise and complementary results by merging signals from different techniques, improving sensitivity and selectivity in analyte quantification.
Implementation Method 1
the first electrode (8) is configured to bind specific analytes of the biological sample
Implementation Method 2
a computing unit (6) connected to the analog-to-digital converter (5) and to the electronic signal-conditioning module (3)
Data Source
AI summary
The present disclosure refers to an electronic biological sample measurement device that uses at least two detection techniques in virtual concurrence to measure the concentration of a target analyte in at least one biological sample. The detection techniques are electrochemical treatment, electro-optical treatment, and field-effect treatment, or combinations in sequence thereof. The measurement device of the present disclosure may combine at least two selected measurement techniques (and up to three techniques) without manually modifying the connections of said device, which is an advantage in that it improves selectivity and sensitivity in the measurement of the analyte.