Multi-Mode Microscopy Illumination With Electrical Switching
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Solution Overview
Problem
Conventional microscopy systems require mechanical movement of optical parts to switch between different illumination modes, resulting in bulkiness and inefficiency.
Innovation Solution
A compact multi-mode illumination system with fixed optical modules for bright-field, fluorescent, and non-coherent illumination, allowing electrical switching between these modes without mechanical mechanisms.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If mechanical movement of optical parts is used to switch between illumination modes, then different illumination modes can be achieved, but the system becomes bulky and complex
Solution Approach 1:
The patent replaces mechanical movement of optical parts with an electrical switching system. Three separate light sources (halogen lamp for bright-field, LED for fluorescent, and cold LED for non-coherent illumination) are electrically switched on and off to select different illumination modes, eliminating the need for mechanical scanners or movable optical components.
Solution Approach 2:
The illumination system is divided into three independent illumination modules, each with its own light source and optical path. This segmentation allows each module to be optimized for its specific function while enabling independent electrical control, avoiding the need for a single complex mechanical switching system.
2Adaptability or versatility
If multiple illumination optics are integrated into one system, then comprehensive sample analysis is enabled, but the system size increases
Solution Approach 1:
The patent merges three different illumination systems (bright-field, fluorescent, and non-coherent illumination) into a single integrated microscopy platform. All three light sources share common optical components such as the objective lens, camera, and sample stage, reducing the overall system volume compared to having separate microscopy systems.
Solution Approach 2:
The microscopy system is designed with multi-functionality to perform multiple types of illumination and analysis (bright-field interference contrast, fluorescent excitation, and non-coherent transmissivity measurement) using a single device. This universal design eliminates the need for multiple separate systems while maintaining comprehensive analytical capability.
3Adaptability or versatility
If mechanical switching mechanisms are used, then illumination mode changes are possible, but operational efficiency decreases
Solution Approach 1:
The patent replaces mechanical switching mechanisms with direct electrical control of light sources. Each illumination mode is activated by simply turning on the corresponding light source (halogen, LED, or cold LED) through electrical switches, enabling rapid mode changes without mechanical movement delays.
Solution Approach 2:
The system is pre-configured with three independently controlled light sources, each optimized for specific illumination modes. This preliminary setup allows immediate switching between modes by electrical control alone, as the optical paths and components are already positioned and ready for each function.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient and compact illumination switching in microscopy, providing bright-field interference contrast, fluorescent excitation, and non-coherent transmissivity measurements with improved operational efficiency.
Implementation Method 1
a parabolic reflector; a first light source disposed at the focus point of the parabolic reflector
Implementation Method 2
a light extraction plate including a light scattering structure disposed on a surface thereof
Implementation Method 3
a right-angle prism and a second light source oriented towards the right-angle prism. The right-angle prism is configured to reflect or redirect light emitted from the second light source towards the sample holder
Data Source
AI summary
A multi-mode illumination system, including: a first illumination module; a second illumination module; and a third illumination module, as disclosed herein.


