Multi-Omics Responder Classification for Personalized Skincare Regimens
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Solution Overview
Problem
Existing skincare treatments lack accuracy in determining responder categories for individuals, leading to suboptimal treatment outcomes due to insufficient use of omics data and dynamic responder category changes over time.
Innovation Solution
A computing system utilizing classifiers for various types of omics data to determine responder categories, which are updated based on clinical signs of aging and skincare regimen measurements, to improve treatment outcomes by personalizing skincare regimens.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If traditional skincare treatments are used without omics data analysis, then the treatment approach is simple and easy to implement, but the accuracy in determining responder categories is low leading to suboptimal treatment outcomes
Solution Approach 1:
The patent segments the complex omics data analysis into multiple independent classifiers, each handling a specific type of omics data (genomics, transcriptomics, proteomics, metabolomics, microbiomics). This segmentation allows the system to process different data types separately and combine results, reducing the complexity burden while maintaining high accuracy in responder category determination.
Solution Approach 2:
The patent introduces classifier models as intermediary components between raw omics data and responder category determination. These classifiers act as mediators that transform complex multi-omics data into actionable predictions, enabling accurate responder categorization without requiring direct complex analysis of all omics data simultaneously.
2Measurement precision
If static responder categories are used, then the classification process is simple, but the accuracy decreases due to dynamic changes in responder categories over time
Solution Approach 1:
The patent implements dynamic responder category determination by continuously updating classifier models with new omics data and clinical measurements over time. The system transitions from static classification to dynamic adaptation, where responder categories evolve as the subject's biological state changes, maintaining high accuracy without requiring excessive repeated measurements.
Solution Approach 2:
The patent incorporates feedback mechanisms where clinical measurements and treatment outcomes are fed back into the classifier models to update and refine predictions. This feedback loop allows the system to learn from actual treatment responses and improve future predictions, reducing the need for frequent re-measurements while maintaining accuracy.
3Reliability
If personalized skincare regimens are developed using omics data, then treatment outcomes are improved, but the complexity of regimen customization increases
Solution Approach 1:
The patent creates a universal platform with multi-functional classifiers that can handle multiple types of omics data and apply to various skincare treatment scenarios. This universal system reduces the complexity of developing personalized regimens by providing a standardized framework that works across different data types and treatment contexts, rather than requiring separate custom solutions for each case.
Data Source
AI summary
In some embodiments, techniques for improving treatment outcomes are provided. A computing system measures at least one skin condition for a subject. The computing system receives a plurality of types of omics data for the subject. For each type of omics data, the computing system uses at least one classifier associated with the type of omics data to determine whether the subject is in at least one responder category. The computing system predicts treatment outcomes for the at least one skin condition for the subject for a plurality treatments based on the at least one responder category. The computing system determines a skincare regimen based on the predicted treatment outcomes.


