Multi-Opening Liquid Injection Tip for Uniform Tissue Heating
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Solution Overview
Problem
Existing hyperthermia treatments face challenges in delivering uniform thermal doses to tumor volumes due to physical and physiological barriers, leading to inefficiencies in cancer treatment.
Innovation Solution
A liquid injection device with a hollow tip featuring multiple circumferentially displaced openings is used to deliver a heated liquid uniformly into tissues, minimizing bleeding risk and ensuring precise thermal dosimetry through a non-cutting edge design, combined with the use of anesthetic and adrenaline to reduce blood flow.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If a single opening is used in the hollow tip, then the device structure is simple, but the liquid cannot spread uniformly in the tissue
Solution Approach 1:
The hollow tip is divided into multiple segments with separate openings distributed around its circumference. This segmentation allows the liquid to be delivered through multiple pathways simultaneously, creating uniform radial spread in the tissue while maintaining a relatively simple overall device structure.
2Ease of operation
If a cutting edge is used for tissue penetration, then penetration is easier, but bleeding risk increases
Solution Approach 1:
Instead of using a conventional cutting edge that mechanically severes tissue, the invention employs a non-cutting edge that relies on tissue elasticity and compression to create penetration. This inverted approach reduces mechanical trauma and bleeding while maintaining penetration capability through alternative mechanisms.
3Reliability
If high temperature is used for hyperthermia treatment, then treatment efficacy is improved, but systemic side effects increase
Solution Approach 1:
The device delivers heat locally through multiple small openings distributed around the hollow tip, creating concentrated thermal zones at the injection site. This local quality approach ensures high treatment efficacy at the target location while minimizing thermal spread to surrounding tissues, thereby reducing systemic side effects.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The device enables uniform heat distribution, reducing bleeding and cooling effects, enhancing treatment efficacy by increasing thermal dose uniformity and minimizing systemic side effects.
Implementation Method 1
The tissue surrounding the ferromagnetic implant is heated by conduction of heat away from the implanted seeds
Implementation Method 2
The energy transferred to the tissue is dependent on the mass of the tissue and is calculated on the basis of the temperature and the volume of the liquid
Implementation Method 3
The needle is penetrating tissue displacing it when introduced and the tissue is returning to its original position when the needle is retracted
Implementation Method 4
combined with the use of anesthetic and adrenaline to reduce blood flow
Data Source
AI summary
A liquid injection device may include an injection tube. The injection tube may extend to a hollow tip with a plurality of openings. At least three circumferentially displaced openings may be provided around the hollow tip below an edge of the hollow tip, and the hollow tip may be provided with a non-cutting edge. A method for performing heat therapy of mammalian tissue may involve inserting an injection tube extending to a hollow tip in a selected position in the tissue. A liquid including at least one anesthetic and adrenaline heated to a temperature of at least 37° C. may be injected through the injection tube and through a plurality of openings below an edge of the hollow tip into the mammalian tissue.