Multi-pole Synchronous Pulmonary Artery RF Ablation Catheter
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Solution Overview
Problem
Current treatments for pulmonary hypertension are limited in efficacy and often come with significant side effects, inappropriate dosage forms, high costs, and unreliable results, making them unsuitable for widespread clinical application.
Innovation Solution
A multi-pole synchronous pulmonary artery radiofrequency ablation catheter is used to target hyper sympathetic activity in the pulmonary artery by blocking sympathetic nerves or damaging baroreceptor structures, employing radiofrequency energy to heat tissue while protecting the vascular intima with cold saline perfusion, allowing for precise and controlled ablation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If radiofrequency ablation is applied to treat pulmonary hypertension, then treatment efficacy is improved, but risk of thermal damage to vascular intima increases
Solution Approach 1:
Cold saline is perfused through the catheter before, during, and after radiofrequency ablation to pre-cool and continuously protect the vascular intima from thermal damage while allowing effective tissue ablation
Solution Approach 2:
Cold saline acts as an intermediary cooling medium between the radiofrequency electrode and the vascular intima, absorbing excess heat and preventing direct thermal injury to the vessel wall
2Productivity
If multi-pole synchronous ablation is used, then operation time is reduced, but device complexity increases
Solution Approach 1:
The catheter incorporates multiple independent electrodes (at least three poles) that can be individually controlled, allowing simultaneous ablation at multiple sites along the pulmonary artery to reduce total procedure time
Solution Approach 2:
The catheter design integrates multiple functions including radiofrequency ablation, cold saline perfusion, and temperature monitoring in a single device, enabling comprehensive treatment while reducing the need for multiple separate interventions
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach effectively reduces pulmonary artery pressure, providing a more successful treatment for pulmonary hypertension with simpler operations, shorter procedure times, and reduced risk to the vascular intima.
Implementation Method 1
multi-pole synchronous pulmonary artery radiofrequency ablation catheter... employing radiofrequency energy to heat tissue
Implementation Method 2
the catheter can be configured to provide cold saline perfusion at or near the ablation site to protect the vascular intima
Data Source
AI summary
Systems, devices, and method for performing pulmonary artery denervation are disclosed. An ablation device is positioned in a pulmonary artery trunk of a patient. Target tissue is ablated in the pulmonary artery trunk under conditions effective to affect a reduction in mean pulmonary artery pressure and systolic pulmonary artery pressure. The target tissue includes at least one of the distal portion of the main pulmonary artery, the proximal portion of the left pulmonary artery, or the proximal portion of the right pulmonary artery.