Multi-Protease Detergent Synergy for Low-Temperature Protein Removal
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Solution Overview
Problem
Current detergents and cleaning agents with single or multiple proteases do not effectively remove protein-containing soiling, especially at low temperatures, and require high protease concentrations, which can be inefficient and costly to develop.
Innovation Solution
Formulating detergents with specifically selected proteases having different activity spectra and sequences, which when combined, exhibit a synergistic effect, enhancing proteolytic activity and cleaning performance at low temperatures with reduced protease content.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If high protease concentrations are used in detergents, then protein-containing soiling removal is improved, but development complexity and cost increase
Solution Approach 1:
The patent combines multiple proteases with different activity spectra into a single detergent composition. This merging of different enzymatic activities creates a synergistic effect that improves protein soil removal reliability without requiring excessively high concentrations of any single protease, thereby reducing development complexity compared to optimizing one high-performance protease alone
Solution Approach 2:
The invention uses a composite enzymatic system comprising at least two different proteases with distinct activity spectra. This composite approach leverages the complementary strengths of different proteases to achieve superior and more reliable protein-containing soiling removal while distributing the development effort across multiple commercially available enzymes rather than creating a single complex protease
2Reliability
If high protease concentrations are used in detergents, then cleaning performance is improved, but cost increases
Solution Approach 1:
By merging multiple proteases with different activity spectra in a detergent composition, the invention achieves enhanced cleaning performance through synergistic interactions. This allows the use of moderate concentrations of each protease rather than requiring very high concentrations of a single protease, thereby reducing the total protease content needed while maintaining or improving cleaning performance
Solution Approach 2:
The invention changes the parameter of protease diversity by introducing multiple proteases with different activity spectra instead of relying on high concentrations of one protease type. This parameter change enables achieving better cleaning performance at lower total protease concentrations by utilizing the complementary actions of different enzymatic specificities
3Reliability
If single protease systems are used in detergents, then formulation simplicity is maintained, but protein removal efficiency at low temperatures is insufficient
Solution Approach 1:
The patent merges multiple proteases with different activity spectra into a single detergent formulation. This combination creates synergistic effects that significantly improve protein removal efficiency at low temperatures, overcoming the limitations of single protease systems while adding only moderate formulation complexity
Solution Approach 2:
The invention changes the formulation parameter by incorporating multiple proteases with different activity spectra and temperature characteristics. This parameter change enables effective protein removal at low temperatures through the complementary thermal and catalytic properties of different proteases, achieving superior performance despite increased formulation complexity
4Reliability
If multiple proteases with different activity spectra are combined, then synergistic effect and cleaning performance are improved, but protease selection complexity increases
Solution Approach 1:
The patent merges multiple proteases with different activity spectra in a detergent composition to achieve synergistic cleaning effects. While this improves cleaning performance, it does increase protease selection complexity as the inventor must identify and combine proteases with complementary activity spectra that work synergistically rather than redundantly
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The combination of proteases with different activity spectra achieves better protein removal than single or additive protease systems, improving cleaning efficiency at low temperatures with reduced protease amounts, thus enhancing washing performance and stability.
Implementation Method 1
They act as nonspecific endopeptidases, meaning they hydrolyze any acid amide bonds found within peptides or proteins
Implementation Method 2
Proteases are among the most technically important enzymes of all... they are classified as serine proteases
Data Source
AI summary
The invention relates to agent compositions, in particular detergents and cleaning agents, which contain a first protease and at least a second protease, optionally a third or more proteases. The invention further relates to cleaning methods, in which said agents are used, to uses of said agents, and to cleaning methods and uses of said proteases.