Multi-sample liquid scattering measurement parallel analysis
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Existing methods for measuring fluid properties in multiple samples are inefficient and lack the capability to simultaneously analyze and derive properties from a large number of samples with high precision.
Innovation Solution
A multi-sample liquid scattering measurement apparatus and method utilizing a coherent light source and detectors to analyze scattered light from multiple samples, allowing for simultaneous measurement and property derivation, with optional environmental control and parallel loading of samples from multi-well plates.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If existing methods are used to measure fluid properties in multiple samples, then measurement capability is provided, but efficiency and processing speed are insufficient
Solution Approach 1:
The system divides the measurement task into multiple independent measurement channels, each handling a separate sample cell. The linear array of sample cells (12A-12N) with associated detectors (16A-16N) allows parallel measurement of multiple samples simultaneously, transforming a sequential process into a parallel one and dramatically increasing throughput while reducing total processing time.
Solution Approach 2:
The invention combines multiple measurement functions into a single integrated system. A single coherent light source (14) illuminates all sample cells simultaneously, and multiple detectors work in parallel to capture scattered light from each sample. This merging of functions into one system achieves high-throughput multi-sample measurement without requiring multiple separate measurement devices.
2Productivity
If multiple samples are analyzed simultaneously, then productivity increases, but measurement precision may be compromised
Solution Approach 1:
The system assigns dedicated detectors to specific sample cells, creating independent measurement channels. Each detector (16A-16N) is positioned to receive scattered light from its corresponding sample cell (12A-12N), ensuring that measurements from multiple samples remain independent and maintain individual precision while enabling simultaneous analysis of many samples.
Solution Approach 2:
The system optimizes the measurement configuration for each sample cell individually. Detectors are positioned at specific angles relative to each sample cell to maximize scattered light collection efficiency. The analysis logic applies sample-specific processing to derive properties from each cell's scattered light pattern, ensuring local optimization of measurement precision for each sample while maintaining overall system productivity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient and precise analysis of multiple fluid samples by detecting scattered light across a large number of samples, providing accurate properties and handling large sample sets with reduced processing time and increased throughput.
Implementation Method 1
detectors are each positioned to detect scattered light resulting from an interaction between light from the coherent light source and one of the cells
Data Source
AI summary
In one general aspect, a multi-sample liquid scattering measurement apparatus is disclosed. It includes a coherent light source having an optical output axis, with sample cells that each include a volume that intersects with the optical output axis. Detectors are each positioned to detect scattered light resulting from an interaction between light from the coherent light source and one of the cells. Light scattering analysis logic is responsive to the detectors and operative to determine a property of a liquid sample in each of the sample cells based on the detected scattered light.