Multi-Substituted Hydroxyapatite Antiperspirant for Skin Irritation

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Solution Overview

Problem

Conventional antiperspirant and deodorant compositions using aluminum-based salts can cause skin irritation due to hyper-acidification and have limited effectiveness, necessitating a safer and more effective alternative.

Innovation Solution

A cosmetic composition utilizing multi-substituted hydroxyapatite with at least two cations such as aluminum, zinc, magnesium, zirconium, titanium, copper, silver, or iron, which provides controlled release of these ions, reducing skin irritation and enhancing antiperspirant and deodorant performance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If aluminum-based salts are used as antiperspirant active ingredients, then perspiration control effectiveness is improved, but skin irritation occurs due to hyper-acidification

Engineering Contradiction:

Improveperspiration control effectivenessVSAvoidskin irritation

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

Hydroxyapatite serves as an intermediary carrier that delivers aluminum and/or zirconium ions to the skin. The hydroxyapatite structure controls the release rate of these ions, preventing sudden hyper-acidification while maintaining effective perspiration control over time. This mediator approach separates the delivery mechanism from the active ingredient, allowing controlled release that mitigates skin irritation.

Inventive Principle:

Principle #24Intermediary (Mediator)

Solution Approach 2:

The invention changes the physical and chemical parameters of aluminum/zirconium delivery by incorporating them into hydroxyapatite crystals. This transformation alters the release kinetics from immediate (causing irritation) to controlled and sustained (reducing irritation while maintaining effectiveness). The hydroxyapatite matrix modifies the solubility and dissolution rate parameters of the active ions.

Inventive Principle:

Principle #35Parameter changes

2Object-affected harmful factors

If mono-substituted hydroxyapatite is used, then some deodorant effect is achieved, but antiperspirant effectiveness is limited

Engineering Contradiction:

Improvedeodorant effectVSAvoidantiperspirant effectiveness

Core Design Contradiction:

Object-affected harmful factorsVSReliability

Solution Approach 1:

The invention merges multiple metal cations (aluminum and/or zirconium) within the hydroxyapatite structure to achieve synergistic effects. This combination provides both deodorant properties (from the hydroxyapatite matrix) and enhanced antiperspirant effectiveness (from the combined action of multiple metal ions), resolving the limitation of mono-substituted versions.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The multi-substituted hydroxyapatite structure achieves multi-functionality by simultaneously providing deodorant activity (malodor adsorption) and antiperspirant activity (sweat gland blocking). The composite structure with multiple metal cations performs multiple functions that single-substituted or separate formulations could not achieve alone.

Inventive Principle:

Principle #6Universality (Multi-functionality)

3Device complexity

If physical association of hydroxyapatite with common antiperspirant salts is used, then formulation simplicity is maintained, but skin irritation and limited effectiveness persist

Engineering Contradiction:

Improveformulation simplicityVSAvoidskin irritation

Core Design Contradiction:

Device complexityVSObject-affected harmful factors

Solution Approach 1:

The invention creates a true composite material where aluminum and/or zirconium ions are incorporated into the hydroxyapatite crystal lattice during synthesis. This composite structure provides controlled release properties and reduced skin irritation, superior to simple physical associations. The composite nature allows the material to maintain formulation simplicity while achieving advanced performance through integrated structure-function design.

Inventive Principle:

Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The multi-substituted hydroxyapatite composition is skin-friendly, long-acting, non-irritant, and effective in reducing perspiration and body odor, with improved bacteriostatic activity and increased malodor adsorption compared to physical associations with other inorganic salts.

Implementation Method 1

hydroxyapatite active are described in FR2812194A1 and US2006/045860A1... multi-substituted hydroxyapatite with at least two cations selected among aluminium, zinc, magnesium, zirconium, titanium, copper, silver or iron... increased malodor adsorption

Methodology Applied

Scientific EffectAdsorption: Adsorption

Implementation Method 2

Deodorants can act as bacteriostatic agents (substances that limit the proliferation of bacterial flora responsible for unpleasant odors)... improved bacteriostatic activity

Methodology Applied

Scientific EffectBacteriostatic effect:

Implementation Method 3

deodorants (that mask the malodors caused by sweat)... adsorbents compounds that form complexes with the molecules responsible for odors, reducing their volatility and therefore limiting their diffusion

Methodology Applied

Scientific EffectComplex formation:

Data Source

PatentEP3946223B1Antiperspirant and deodorant compositions

Publication Date: 2023.06.07 KALICHEM ITALA

AI summary

An antiperspirant and deodorant composition comprising a hydroxyapatite multi- substituted with at least two cations selected among aluminium, zinc, magnesium, zirconium, titanium, copper, silver or iron.