Multi-Wavelength Optical Sample Classification for PRP
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Solution Overview
Problem
Current optical classification methods for samples like platelet-rich plasma (PRP) are unable to accurately distinguish between cells due to low resolution, particularly for samples with similar colors and light transmittances, leading to potential misjudgment.
Innovation Solution
A sample classification device and system that uses multiple light-emitting devices emitting different wavelengths, with an optical sensing device to capture reflected light spectra, which are then compared to a standard database to determine the sample type, incorporating a carrier, detection modules, and a pipeline system for accurate classification.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If optical penetration and refraction sensing approaches are used for classifying separated cells, then the classification process can be performed, but the resolution is low and accurate distinction between cells such as platelets, plasma, red blood cells and white blood cells is impossible
Solution Approach 1:
The patent changes the measurement parameter from simple optical penetration/refraction to reflected light spectrum analysis at multiple wavelengths. By measuring samples at different wavelengths (e.g., 450nm, 530nm, 630nm, 680nm) and analyzing spectral characteristics, the system captures detailed optical properties that enable accurate differentiation between cell types with similar appearances.
Solution Approach 2:
The patent transitions from single-parameter optical measurement to multi-dimensional spectral analysis. Instead of relying on a single optical property, the system measures reflected light intensity across multiple wavelengths, creating a spectral fingerprint for each sample type that provides richer information for accurate classification.
2Reliability
If it is difficult to distinguish samples that have similar colour and light transmittances as PRP and plasma, then misjudgement is likely to occur
Solution Approach 1:
The patent measures reflected light intensity at multiple specific wavelengths (450nm, 530nm, 630nm, 680nm) to capture the spectral characteristics of different samples. This multi-wavelength approach reveals subtle differences in optical properties that are not visible at single wavelengths, enabling reliable distinction between PRP and plasma despite their similar appearance.
Solution Approach 2:
The system compares measured spectral data against pre-established reference spectra for different sample types. This feedback mechanism allows the system to identify and correct potential misjudgments by matching observed spectral patterns with known reference patterns, thereby improving classification reliability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for precise determination of sample types by analyzing reflected light spectra, reducing misclassification errors and improving accuracy in distinguishing between similar samples.
Implementation Method 1
The first optical sensing device receives the reflected light generated by the first light-emitting device and the second light-emitting device irradiating the sample
Implementation Method 2
obtain the reflected light spectrum of the sample. The reflected light spectrum of the sample is compared with the standard reflected light spectrum database
Data Source
AI summary
A sample classification device including a carrier, a first detection module, and a sample pipeline is provided. The first detection module includes a first light-emitting device, a second light-emitting device, and a first optical sensing device. The first light emitting device is located on the carrier and used to emit light of a first wavelength. The second light emitting device is located on the carrier and used to emit light of a second wavelength. The first wavelength is different from the second wavelength. The first optical sensing device is located on the carrier and between the first light emitting device and the second light emitting device. The sample pipeline is located above the carrier and passes above the first optical sensing device.