Multicoil NMR Detection with High-Impedance Preamplifiers

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Solution Overview

Problem

Conventional NMR systems are not practical for multicoil NMR detection and imaging at low operating frequencies due to mutual coupling between adjacent coils and lack of mechanisms for efficient switching and signal isolation, particularly in low-field applications where long transmission line segments and low self-impedance detection coils complicate signal processing.

Innovation Solution

A multicoil NMR detection and imaging apparatus with high input impedance preamplifier circuits, actively-controlled relays, and a flexible coil selection mechanism that isolates noise and suppresses current flow between coils, allowing for efficient transmission and reception on multiple coils with various polarities and combinations, eliminating the need for quarter-wavelength transmission line segments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If multiple detection coils are used in low-field NMR, then detection sensitivity and imaging capability are improved, but mutual coupling between adjacent coils increases

Engineering Contradiction:
Improvedetection sensitivityVSAvoidmutual coupling between coils
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent divides the detection system into multiple independent detection coils, each with its own preamplifier and switching circuitry. This segmentation allows each coil to be optimized independently while reducing mutual coupling through physical and electrical isolation strategies.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent introduces preamplifiers with high input impedance as intermediary components between the detection coils and the signal processing system. These preamplifiers act as buffers that minimize current draw from the coils, thereby reducing mutual coupling effects while maintaining signal integrity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-affected harmful factors

If quarter-wavelength transmission line segments are used to isolate transmitter noise, then noise isolation is improved, but device complexity and length requirements increase

Engineering Contradiction:
Improvetransmitter noiseVSAvoidtransmission line segment requirements
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent extracts the noise isolation function from the transmission line structure and implements it through active switching circuits and preamplifier design. This removes the requirement for quarter-wavelength transmission line segments while achieving the same noise isolation objective through electronic means.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces the mechanical/electrical solution of quarter-wavelength transmission line segments with electronic switching and impedance matching circuits. This substitution eliminates the length and frequency constraints associated with transmission line-based noise isolation.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Object-generated harmful factors

If preamplifiers with low input impedance are used to reduce current flow, then mutual coupling is reduced, but signal gain is lost

Engineering Contradiction:
Improvecurrent flow between coilsVSAvoidsignal gain
Core Design Contradiction:
Object-generated harmful factorsVSPower

Solution Approach 1:

The patent changes the input impedance parameter of the preamplifiers to be high rather than low. This parameter change allows the preamplifiers to present a high impedance load to the coils, minimizing current flow and mutual coupling while simultaneously providing high signal gain through the preamplifier's internal amplification stages.

Inventive Principle:
Principle #35Parameter changes

4Object-affected harmful factors

If switching circuits are added to isolate transmitter noise, then noise isolation is improved, but device complexity increases

Engineering Contradiction:
Improvetransmitter noise interferenceVSAvoidswitching circuitry
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent designs switching circuits that serve multiple functions: they isolate transmitter noise during reception, enable selective activation of individual coils, and provide transmit/receive mode switching. This multi-functionality reduces the need for separate dedicated circuits for each function, thereby limiting the increase in overall device complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution reduces mutual coupling, provides high signal gain, and effective noise isolation during receive mode, enabling efficient multicoil NMR detection and imaging at low static field strengths and frequencies, while allowing flexible routing of NMR excitation pulses through individual or combined coils.

Implementation Method 1

The preamplifier circuits have an input impedance substantially greater than the impedance of each respective detection coil at the intended operating frequency, thereby suppressing current flow, and hence suppressing mutual coupling, among the plurality of detection coils during receive mode

Methodology Applied
Scientific EffectElectrical Impedance: Electrical Impedance Tomography

Implementation Method 2

The switching elements are opened during receive mode to prevent high voltages and currents on the transmit coil or coils from damaging the receive electronics

Methodology Applied
Scientific EffectElectromagnetic Induction: Electromagnetic Induction

Implementation Method 3

NMR systems have been in use for many years and can be used to provide imaging and/or analysis of a sample being tested

Methodology Applied
Scientific EffectNuclear Magnetic Resonance: Electromagnetic Induction

Data Source

PatentUS8451004B2Multicoil low-field nuclear magnetic resonance detection and imaging apparatus and method
Publication Date: 2013.05.28 VISTA CLARA
  • US8451004B2 patent drawing
  • US8451004B2 patent drawing
  • US8451004B2 patent drawing

AI summary

A multicoil NMR detection and imaging apparatus allows multicoil NMR detection and imaging to be performed efficiently at low operating frequencies. The apparatus comprises an AC voltage generator, a transmit switching circuit, a coil switching network, an array of two or more detection coils, a set of receive switching circuits with one switching circuit for each detection coil, and a set of preamplifier circuits with input impedance substantially greater than the impedance of each respective detection coil at the intended operating frequency. The AC generator produces an alternating current waveform that is routed through one of more detection coils during transmit mode while the preamplifier circuits are isolated from the detection coil(s). During receive mode the AC generator is isolated from the detection coils to prevent noise from the transmitter from degrading the quality of received signals.