Multi-Layer Polymer Bonding for PVC and Non-PVC CAPD Components

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Solution Overview

Problem

Total PVC container-closure systems for continuous ambulatory peritoneal dialysis (CAPD) face public and regulatory concerns due to plasticizers, while total non-PVC systems are more expensive. A cost-effective hybrid system combining non-PVC and PVC components is needed.

Innovation Solution

A multi-layer article with a polymer blend comprising propylene and α-olefin copolymer and carbon monoxide-containing polyolefin-based copolymer is used to bond non-PVC and PVC components, allowing autoclave and solvent bonding, ensuring adhesion without bisphenol A release.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If total non-PVC materials are used for all components, then health safety concerns are resolved, but system cost increases

Engineering Contradiction:
Improvehealth safetyVSAvoidsystem cost
Core Design Contradiction:
Object-affected harmful factorsVSEase of manufacture

Solution Approach 1:

The patent applies local quality by differentiating material selection based on functional requirements: non-PVC materials are used specifically for components contacting dialysis solution during sterilization (injection molded parts, tubing interior), while PVC is used for non-contact components. This localized application resolves health concerns for critical components while maintaining cost-effectiveness for other parts.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The system is segmented into distinct material zones: non-PVC segments for solution-contact components and PVC segments for non-contact components. This segmentation allows each segment to be optimized independently for its specific function, enabling the hybrid approach that balances safety and cost.

Inventive Principle:
Principle #1Segmentation

2Adaptability or versatility

If non-PVC injection molded parts are bonded to PVC tubing, then hybrid system is formed, but adhesion strength is insufficient

Engineering Contradiction:
Improvehybrid system compatibilityVSAvoidbond strength
Core Design Contradiction:
Adaptability or versatilityVSStrength

Solution Approach 1:

The patent introduces an intermediary bonding approach using solvent bonding with cyclohexanone that temporarily dissolves both non-PVC and PVC materials at the interface, creating a molecular-level bond. This intermediary chemical process enables strong adhesion between incompatible materials that cannot be bonded by conventional mechanical or thermal methods alone.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The bonding process utilizes parameter changes by controlling solvent concentration, temperature, and exposure time to achieve optimal bond strength. The solvent bonding parameters are carefully adjusted to dissolve sufficient material for bonding while maintaining structural integrity of both non-PVC and PVC components.

Inventive Principle:
Principle #35Parameter changes

3Object-affected harmful factors

If non-PVC components are used, then autoclave bonding is required, but bonding reliability during steam sterilization is compromised

Engineering Contradiction:
Improvesterilization compatibilityVSAvoidbond reliability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The patent applies preliminary action by pre-forming strong solvent bonds between non-PVC and PVC components before sterilization. This preliminary bonding creates a robust connection that can withstand the thermal and mechanical stresses of autoclave sterilization, ensuring bond reliability is established before the sterilization process begins.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The solvent bonding process provides beforehand cushioning by creating a chemical bond that acts as a buffer against the stresses of subsequent sterilization. This pre-established bond strength compensates for the potential weakening effects of heat and moisture during autoclave processing.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The hybrid system provides a cost-effective solution with improved adhesion strength between non-PVC and PVC components, maintaining performance during steam sterilization and avoiding health risks from bisphenol A.

Implementation Method 1

PVC-based injection molded parts are frequently connected with PVC tubing by solvent bonding or radio frequency energy

Methodology Applied
Scientific EffectSolvent bonding: Solvation

Implementation Method 2

Non-PVC injection molded parts can be connected with non-PVC tubing by autoclave heat bonding during steam sterilization

Methodology Applied
Scientific EffectAutoclave heat bonding: Heating

Implementation Method 3

maintaining performance during steam sterilization

Methodology Applied
Scientific EffectThermal stability: Heat Treatment

Data Source

PatentEP4729577A2Multi-layer articles and methods for producing the same
Publication Date: 2026.04.22 VANTIVE US HEALTHCARE LLC
  • EP4729577A2 patent drawingFigure 1

AI summary

The present disclosure provides multi-layer articles that comprise a polyolefin component and a polymer blend attached to the polyolefin component, wherein the polymer blend includes (1) a propylene and α-olefin copolymer in an amount from about 15% to about 70% by weight of the polymer blend, and (2) a carbon monoxide-containing polyolefin-based copolymer in an amount from about 25% to about 85% by weight of the polymer blend. The polymer blend has an extractables fraction with pH higher than 5. Also provided are methods of bonding a first layer comprising polyvinyl chloride to a second layer comprising the disclosed polymer blend.