Multiline Syringe Dispenser Layout for Dense Plate Pipetting
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Solution Overview
Problem
Existing multichannel dispensing devices face limitations in plunger diameter increase due to hole pitch constraints, leading to challenges in dispensing varying amounts efficiently and accurately.
Innovation Solution
A dispenser design with syringes arranged in multiple lines and increased outer diameter housing, allowing for larger plungers and flexible dispensing ranges from small to large volumes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If the plunger diameter is increased to dispense greater amounts in shorter time, then dispensing speed and productivity are improved, but the device cannot be applied to high-hole-density sample plates due to pitch width limitations
Solution Approach 1:
The patent transitions from a single-line arrangement to a multi-line arrangement of syringes, utilizing two-dimensional spatial configuration. This allows the plunger diameter to exceed the pitch distance between dispensing tips while maintaining compatibility with high-hole-density plates through strategic positioning of multiple syringe lines.
Solution Approach 2:
The dispensing system is divided into multiple syringes arranged in multiple lines, with each syringe responsible for specific dispensing tasks. This segmentation allows independent optimization of each syringe's plunger diameter while collectively achieving both high productivity and adaptability to dense plate configurations.
2Quantity of substance
If the plunger diameter is increased, then a greater amount of solution can be dispensed with shorter plunger movement distance, but the device complexity increases
Solution Approach 1:
Multiple syringes are merged into a single integrated multichannel dispensing device with a unified drive system. This combining approach allows each syringe to have a large plunger diameter for high-volume dispensing while the shared control mechanism maintains overall device simplicity.
3Measurement precision
If the plunger diameter is decreased to improve solution amount accuracy, then dispensing precision is improved, but dispensing time increases for greater amounts
Solution Approach 1:
The system uses multiple syringes working in parallel, where each syringe can perform partial dispensing operations. This allows the use of larger plungers that move shorter distances for each individual syringe while collectively achieving both accuracy and speed through coordinated multi-syringe operation.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables efficient dispensing of varying amounts with improved accuracy and reduced movement time, while maintaining a compact design and simplified drive system.
Implementation Method 1
a drive motor that drives at least one of the plungers
Data Source
AI summary
A multichannel dispenser 100 includes a plurality of syringes 103 each of which includes a plunger 101 and a housing 102, a drive motor 104 that drives at least one of the plungers 101, tip end portions 106 to which dispensing tips 105 are to be attached, and tubes 107A, 107B causing the syringes 103 and the tip end portions 106 to communicate with each other. The outer diameter 109 of the housing 102 is greater than a pitch distance 108 between the dispensing tips 105, and the plurality of syringes 103 is arranged in multiple lines. Thus, it is possible to increase a plunger diameter as compared to the related art, and to perform dispensing in amounts ranging from a slight amount to a great amount.