Multi-Material Bone Implants via Additive Manufacturing

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Solution Overview

Problem

Traditional bone joining implants are limited in controlling mechanical properties, leading to potential bone resorption due to stiffness mismatch and inadequate fracture healing due to stiffness or flexibility issues, as they are typically made from a single material.

Innovation Solution

The development of multi-material implants fabricated using additive manufacturing techniques, where different regions with varying material properties are integrated to mimic the biomechanical properties of bone, allowing for tailored stiffness and flexibility to enhance fracture healing and stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Strength

If bone joining implants are made from single material with high stiffness, then strength and stability are improved, but bone resorption occurs due to stiffness mismatch

Engineering Contradiction:
Improveimplant strengthVSAvoidbone resorption
Core Design Contradiction:
StrengthVSObject-affected harmful factors

Solution Approach 1:

The implant incorporates regions with different material properties: a first region with higher stiffness for strength and stability, and a second region with lower stiffness to match bone mechanics and prevent resorption. This spatial variation in material quality resolves the contradiction between needing high strength and avoiding bone resorption.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The implant is constructed as a composite structure with at least two different materials or material combinations, each providing different mechanical properties. This composite approach allows simultaneous optimization of strength (first region) and bone compatibility (second region), resolving the stiffness mismatch problem.

Inventive Principle:
Principle #40Composite materials

2Object-affected harmful factors

If bone joining implants are made from single material with low stiffness, then bone compatibility is improved, but fracture healing fails due to excessive movement or implant breakage

Engineering Contradiction:
Improvebone compatibilityVSAvoidfracture healing reliability
Core Design Contradiction:
Object-affected harmful factorsVSReliability

Solution Approach 1:

The implant design assigns different stiffness characteristics to different regions: the second region has lower stiffness for bone compatibility, while the first region has higher stiffness to provide structural support and prevent implant breakage. This local differentiation resolves the contradiction between bone compatibility and fracture healing reliability.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

By using composite materials with different mechanical properties in different regions, the implant achieves both bone compatibility (through the more flexible second region) and structural reliability (through the stiffer first region), preventing both excessive movement and implant failure.

Inventive Principle:
Principle #40Composite materials

3Adaptability or versatility

If bone joining implants use multiple components for alignment, then alignment capability is improved, but manufacturing complexity increases

Engineering Contradiction:
Improvealignment capabilityVSAvoidimplant structure complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The implant integrates multiple functional components into a single monolithic structure fabricated by additive manufacturing. The first and second regions with different material properties are combined in one component that provides both alignment and load-bearing functions, reducing the number of separate parts while maintaining alignment capability.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The multi-material implant structure serves multiple functions simultaneously: alignment of fracture fragments, load-bearing support, and promotion of bone healing. The different material regions provide different functions within a single component, reducing overall device complexity while maintaining versatility.

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Ease of manufacture

If bone joining implants are made from single piece of stock material, then manufacturing simplicity is maintained, but control over mechanical properties is limited

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidmechanical property control
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The additive manufacturing process enables precise control over material parameters and distribution throughout the implant. Different materials or material combinations can be strategically placed in different regions to achieve specific mechanical properties, while the process remains relatively simple and integrated, resolving the contradiction between manufacturing ease and property control.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The multi-material implants provide improved stability and flexibility, promoting optimal bone healing by distributing load effectively and reducing the risk of bone resorption, thereby enhancing the biomechanical compatibility with the bone being repaired.

Implementation Method 1

solidifying at least a portion of a first layer of curable powder... solidifying at least a portion of the second layer onto the first solid region

Methodology Applied
Scientific EffectPhotopolymerisation: Photopolymerisation

Data Source

PatentEP3045148B1Intergrated multi-material implants and methods of manufacture
Publication Date: 2018.11.14 SYNTHES GMBH
  • EP3045148B1 patent drawingFigure 1A~2B
  • EP3045148B1 patent drawingFigure 3A~3D
  • EP3045148B1 patent drawingFigure 4A~4H

AI summary

Provided are methods and systems for fabricating multimaterial bodies in a layer-wise fashion, which bodies may be used bone-stabilizing implants. The multimaterial bodies include rigid and flexible portions that are integrally formed with one another. The multimaterial bodies may be softened or stiffened in specific areas to match the biological or anatomical features of a bone.