Multimodal Cardiac Therapy System Reducing Transthoracic Resistance

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Solution Overview

Problem

Current transthoracic cardioversion and pacing techniques for cardiac dysrhythmias, such as atrial fibrillation, have limited success rates due to inadequate current flow across the myocardium, largely attributed to high transthoracic resistance, which is not effectively reduced by existing methods like self-adhesive electrode pads and lack of mechanical intervention.

Innovation Solution

A Cardiac Electrical Therapy Efficacy Enhancement System (CETEES) that integrates automatic mechanical, pneumatic, acoustic, and electrophysiologic capabilities with electrical countershock or pacing, using increased contact pressure, synchronization with ventilation, multiple current paths, vibrational or acoustic energy, and vagal stimulation to optimize treatment parameters and enhance current flow.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If self-adhesive electrode pads are used for transthoracic cardioversion or pacing, then ease of operation is improved, but transthoracic resistance is not effectively reduced, limiting current flow

Engineering Contradiction:
Improveease of operationVSAvoidsuccess rate of cardioversion or pacing
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The system performs preliminary actions by mechanically compressing the thorax before electrical therapy delivery to reduce transthoracic resistance, and by delivering vibrational/acoustic energy to the myocardium beforehand to enhance tissue permeability to electrical current, thereby preparing the physiological conditions for more effective cardioversion or pacing

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system applies vibrational or acoustic energy directly to the myocardium through the thorax, causing mechanical vibration of cardiac tissues that enhances current flow during electrical therapy and improves the effectiveness of cardioversion or pacing by disrupting abnormal electrical patterns

Inventive Principle:
Principle #18Mechanical vibration

2Reliability

If higher electrical energy is delivered to overcome high transthoracic resistance, then current flow may be improved, but risk of tissue damage and patient discomfort increases

Engineering Contradiction:
Improvecurrent flow across myocardiumVSAvoidtissue damage and patient discomfort
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system changes physiological parameters by mechanically reducing transthoracic resistance and applying vibrational energy to the myocardium, thereby lowering the electrical energy threshold required for successful cardioversion or pacing and reducing the risk of tissue damage and patient discomfort from high-energy shocks

Inventive Principle:
Principle #35Parameter changes

3Reliability

If mechanical compression of the thorax is applied to reduce transthoracic resistance, then current flow is improved, but device complexity increases

Engineering Contradiction:
Improvecurrent flowVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system integrates multiple functions into a single device including mechanical thoracic compression, vibrational/acoustic energy delivery, and electrical therapy delivery, allowing one device to perform multiple therapeutic actions that collectively improve current flow and cardioversion effectiveness without requiring separate specialized devices

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly increases the probability of successful cardioversion or pacing by reducing transthoracic resistance and improving current flow, thereby enhancing the efficacy of electrical therapies for patients with perfusing circulation.

Implementation Method 1

Both cardioversion and pacing can work by delivering an electric shock through the thorax of a patient

Methodology Applied
Scientific EffectElectrical conduction: Conduction (electrical)

Implementation Method 2

The device can include a mechanical compression subsystem that can be applied to a patient's thorax

Methodology Applied
Scientific EffectMechanical compression: Compression

Implementation Method 3

The device can include a vibrational or acoustic energy emitter that can be applied to a patient's thorax or abdomen

Methodology Applied
Scientific EffectVibrational energy: Vibration

Data Source

PatentEP4335488A1A multimodal device and method to increase the efficacy of transthoracic cardioversion or cardiac pacing in patients with perfusing rhythms
Publication Date: 2024.03.13 PARADIS NORMAN ALAN
  • EP4335488A1 patent drawingFigure 1
  • EP4335488A1 patent drawingFigure 2
  • EP4335488A1 patent drawingFigure 3

AI summary

The invention disclosed here relates in general to the field of medical devices. In particular, to devices and methods for improving the clinical outcome of patients suffering from cardiac dysrhythmias without cardiac arrest. This method and/or device integrates mechanical, pneumatic, acoustic and/or electrophysiologic capabilities with electrical countershock or pacing capabilities such that the probability of successful cardioversion or pacing is increased. The sequence, forces, and electrical properties of the subsystems can be computer controlled and adjusted in response to biomarker inputs. A Cardiac Electrical Therapy Efficacy Enhancement System (100) includes a Transthoracic Cardioverter Pacer TCP (102) and an electrode contact force enhancer (107) adapted to press on an electrode of the TCP (102). A controller (101) synchronizes the TCP (102) and the electrode contact force enhancer (107) so that the TCP (102) administers an electrical discharge in synchrony with the application of force to the TCP electrode by the electrode contact force enhancer (107).