Multi-Modal Polarized Imaging Apparatus for Soft Tissue Identification

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Solution Overview

Problem

Current clinical systems lack the capability to safely and specifically identify soft tissues, such as nerves, in real-time during surgical procedures, leading to potential damage or misidentification.

Innovation Solution

A multi-modal imaging apparatus that concurrently provides visible and near-infrared (NIR) polarized images using a combination of a light source, polarizers, and image sensors, allowing for real-time imaging and improved tissue differentiation by adjusting polarization angles and filtering to enhance image contrast and visibility of soft tissues.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional imaging systems are used during surgery, then the system is simple and easy to operate, but the ability to identify soft tissues such as nerves in real-time is insufficient

Engineering Contradiction:
Improvetissue identification accuracyVSAvoidimaging system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent combines multiple imaging modalities (visible light imaging and NIR imaging) into a single integrated system. The visible light image generator and NIR image generator are merged to provide complementary tissue information simultaneously, improving soft tissue identification accuracy while maintaining a unified device structure that manages complexity through integration rather than separate systems

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The patent extends imaging into the near-infrared spectral dimension beyond the visible range. By adding NIR imaging capability to the conventional visible light imaging, the system accesses additional tissue contrast mechanisms and optical properties that are not visible to the human eye, thereby improving tissue differentiation without requiring fundamentally new imaging principles

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Reliability

If multiple imaging modalities are integrated to improve tissue visibility, then tissue identification capability is enhanced, but the device complexity increases

Engineering Contradiction:
Improvesurgical safetyVSAvoidmulti-modal imaging system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The imaging system is designed with multi-functional capabilities where a single integrated apparatus performs both visible light imaging and NIR imaging functions. The light source, imaging optics, and processing system are configured to support multiple imaging modes, reducing the need for separate dedicated systems and thereby managing complexity while maintaining high surgical safety through improved tissue identification

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent introduces image processing circuitry as an intermediary that receives raw images from both visible and NIR modalities, processes them through fusion algorithms, and generates enhanced composite images. This intermediary processing layer integrates the information from multiple sources systematically, improving reliability through data fusion while managing system complexity through structured signal processing rather than hardware proliferation

Inventive Principle:
Principle #24Intermediary (Mediator)

3Illumination intensity

If polarization angles are adjusted to enhance image contrast, then soft tissue visibility is improved, but the imaging process time increases

Engineering Contradiction:
Improveimage contrastVSAvoidimaging process time
Core Design Contradiction:
Illumination intensityVSLoss of time

Solution Approach 1:

The system maintains continuous imaging operation where visible light and NIR images are captured simultaneously or in rapid succession rather than requiring sequential angle adjustments. The polarization enhancement is achieved through continuous polarization filtering in the optical path rather than discrete angular adjustments, eliminating dead time between measurements and maintaining continuous useful imaging action

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The polarization filters and optical elements are pre-configured in the imaging system before surgery begins. The polarization angles and filter orientations are set in advance to optimize for soft tissue contrast, eliminating the need for time-consuming real-time adjustments during critical surgical procedures. This preliminary configuration ensures optimal contrast is available immediately when needed

Inventive Principle:
Principle #10Preliminary action

4Loss of information

If visible and NIR light ranges are both captured, then tissue differentiation capability is improved, but the data processing complexity increases

Engineering Contradiction:
Improvetissue information completenessVSAvoidimage processing complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The image processing is segmented into distinct functional modules: visible light image processing, NIR image processing, and fusion processing. Each module handles specific aspects of the multi-modal data independently, organizing the complex processing task into manageable segments that can be executed systematically and reduce overall processing complexity through modular architecture

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system extracts and separates the unique tissue information contained in each spectral range (visible and NIR) before fusion. By extracting the complementary information from each modality and processing them independently through dedicated algorithms, the system preserves complete tissue information while managing processing complexity through selective extraction and targeted processing of specific information content from each imaging modality

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables safe and specific real-time identification of soft tissues during surgery, reducing the risk of damage and improving surgical precision by enhancing image contrast and visibility through the integration of visible and NIR light with polarization techniques.

Implementation Method 1

The first polarizer is coupled to the light source, and can pass first polarized light from the output light beam and toward a sample along the optical pathway. The second polarizer is arranged along the optical pathway between the sample and the image sensor, and can pass second polarized light from the reflected light and toward the image sensor.

Methodology Applied
Scientific EffectPolarization: Polarisation

Implementation Method 2

The filter is arranged along the optical pathway and can selectively pass the reflected light in a visible light range and NIR light range (or wavelengths) toward the image sensor.

Methodology Applied
Scientific EffectOptical filtering: Filter (optical)

Implementation Method 3

The control circuitry collects the image data by causing the first and second polarizers to adjust to the different polarization angles, resulting in optical reflections of birefringence from portions of the tissue sample to be focused or discriminated when aligned to a polarization of collimated incident light.

Methodology Applied
Scientific EffectBirefringence: Birefringence

Data Source

PatentUS20220125280A1Apparatuses and methods involving multi-modal imaging of a sample
Publication Date: 2022.04.28 SRI INTERNATIONAL
  • US20220125280A1 patent drawing
  • US20220125280A1 patent drawing
  • US20220125280A1 patent drawing

AI summary

An example apparatus includes a light source, first and second polarizers, an image sensor, a filter, and control circuitry. The light source outputs a light beam, and the first polarizer passes first polarized light from the output light beam and toward a sample. The image sensor collects light reflected from the sample responsive to the passed first polarized light. The second polarizer passes second polarized light from the reflected light and toward the image sensor. The filter selectively passes the reflected light in a visible light range and near infrared range (NIR) light range toward the image sensor. The control circuitry causes the first and second polarizers to adjust to different polarization angles, and collects the image data of the sample from the reflected light.