Multimodal PPG Sensor for Neonatal SpO2 Reliability

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Solution Overview

Problem

Existing pulse oximetry technologies face challenges in obtaining reliable SpO2 measurements in newborns due to spatial and temporal variations in skin physiology, leading to movement artefacts and inaccurate readings, which can be critical in neonatal care where timely monitoring is essential.

Innovation Solution

A photoplethysmography device with a multimodal measurement system that combines DC light ratio analysis at different wavelengths, capacitive sensing, pressure sensing, and lens-based opto-spatial reduction to determine the reliability of SpO2 measurements, ensuring proper sensor placement and contact pressure, thereby improving measurement accuracy and reliability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the sensor is placed on the neonate's skin with sufficient contact pressure to ensure reliable measurement, then measurement reliability is improved, but skin blanching may occur

Engineering Contradiction:
Improvemeasurement reliabilityVSAvoidskin blanching
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system continuously monitors the PPG signal quality and provides feedback to adjust the contact pressure dynamically. When the sensor detects poor signal quality, it automatically increases contact pressure; when signal quality is adequate, it reduces pressure to prevent skin blanching. This closed-loop control resolves the contradiction between ensuring reliable measurement and avoiding skin damage.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The contact pressure is made dynamic rather than static. The system adjusts the pressure in real-time based on signal quality metrics, transitioning between different pressure states as needed. This dynamic adjustment allows the system to optimize between measurement reliability and skin safety at any given moment.

Inventive Principle:
Principle #15Dynamics

2Measurement precision

If the sensor placement is optimized for accurate SpO2 measurement, then measurement precision is improved, but movement artefacts may occur due to improper fit

Engineering Contradiction:
ImproveSpO2 measurement precisionVSAvoidmeasurement reliability
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The system uses feedback from the PPG signal to continuously monitor placement quality. When movement or improper fit is detected through signal degradation, the system provides feedback to adjust the sensor position or contact pressure, thereby maintaining both precision and reliability despite neonatal movement.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The system performs preliminary assessment of signal quality upon initial placement and continuously monitors during measurement. This preliminary and continuous monitoring allows for early detection of placement issues and corrective action before inaccurate measurements are recorded, maintaining both precision and reliability.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If multiple measurement modalities are integrated to improve measurement reliability, then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improvemeasurement reliabilityVSAvoidmeasurement system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines multiple measurement modalities (PPG, DC light ratio, capacitance, pressure sensing) into a single integrated sensor unit. By merging these functions into one cohesive device with shared processing and control systems, the overall complexity is managed more effectively than separate devices would be, while still achieving improved reliability through multi-modal measurement.

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combined modalities enhance the accuracy and reliability of SpO2 measurements by correctly positioning the sensor on the neonate's skin, reducing movement artefacts and providing contextual information for adjusting the sensor's fit, leading to more trustworthy and precise readings.

Implementation Method 1

a light emitter and a light detector configured to detect the light from the light emitter after it has been attenuated by tissue comprising blood vessels

Methodology Applied
Scientific EffectLight attenuation by tissue: Absorption (EM radiation)

Implementation Method 2

When the cardio pulse arrives, more light is absorbed in the increasing blood volume and, as a result, the level of light detected is reduced. The time-varying optical signal that is detected is called the Photoplethysmogram (PPG)

Methodology Applied
Scientific EffectPhotoplethysmography: Absorption (EM radiation)

Implementation Method 3

By measuring a PPG at different wavelengths, a level of oxygen saturation in the haemoglobin can be detected due to the different absorption coefficient of Hb (de-oxygenated haemoglobin) and HbO2 (oxygenated haemoglobin) as a function of wavelength

Methodology Applied
Scientific EffectDifferential light absorption by haemoglobin: Absorption (EM radiation)

Data Source

PatentUS20230039857A1Improved PPG measurement
Publication Date: 2023.02.09 SUREPULSE MEDICAL LTD
  • US20230039857A1 patent drawing
  • US20230039857A1 patent drawing
  • US20230039857A1 patent drawing

AI summary

A device is disclosed comprising: an optical physiological sensor and a further measurement system. The optical physiological sensor comprises a light emitter and a light detector configured to detect the light from the light emitter after it has been attenuated by tissue comprising blood vessels. The optical physiological sensor is configured to determine the value of a physiological parameter from the detected light. The further measurement system is configured to determine when the value of the physiological parameter is likely to be reliable. The further measurement system comprises at least one measurement subsystem, each measurement subsystem employing a different measurement modality that is also different to a measurement modality used to determine the value of the physiological parameter.