Multimodal Sensory Stimulation for Sleep Entrainment

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Solution Overview

Problem

Current pharmacologic interventions for insomnia often lead to tolerance and dependence, necessitating non-pharmacologic solutions for effective long-term management of sleep disorders.

Innovation Solution

Delivery of multimodal sensory stimuli, including visual, tactile, and auditory stimuli at synchronized frequencies between 1 and 60 Hz, with adjustable intensity, and synchronized with brain oscillations measured by EEG, to promote sleep through a device comprising sensory delivery components and a controller module.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If pharmacologic intervention is used for insomnia treatment, then sleep promotion effectiveness is improved in short term, but tolerance and dependence develop leading to reduced effectiveness over time

Engineering Contradiction:
Improvesleep promotion effectivenessVSAvoidlong term treatment sustainability
Core Design Contradiction:
ReliabilityVSDuration of action of stationary object

Solution Approach 1:

The patent replaces pharmacologic (chemical) intervention with a physical stimulation system using light and sound stimuli delivered through optical and acoustic transducers. This substitution eliminates the tolerance and dependence issues associated with pharmacologic agents while maintaining sleep promotion effectiveness through non-invasive sensory stimulation at specific frequencies

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The system employs periodic sensory stimulation delivered at specific frequencies (e.g., 40 Hz gamma frequency) to entrain brain oscillations. This rhythmic, periodic action targets sleep-regulating neural circuits without the adaptive resistance that develops with continuous pharmacologic exposure, thereby sustaining effectiveness over long term use

Inventive Principle:
Principle #19Periodic action

2Device complexity

If single modal sensory stimulation is used, then device complexity is reduced, but sleep promotion effectiveness is insufficient compared to multimodal approaches

Engineering Contradiction:
Improvenumber of sensory delivery componentsVSAvoidsleep promotion effectiveness
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent combines multiple sensory delivery components (optical transducer for light stimuli, acoustic transducer for sound stimuli) into a single integrated device. These components work synergistically to deliver multimodal stimulation that targets multiple neural pathways simultaneously, achieving superior sleep promotion effectiveness while maintaining manageable device complexity through unified control

Inventive Principle:
Principle #5Merging (Combining)

3Ease of operation

If fixed intensity sensory stimulus is used, then ease of operation is improved, but adaptability to individual subject needs is reduced

Engineering Contradiction:
Improvestimulus delivery simplicityVSAvoidadjustment to individual subject requirements
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The system incorporates adjustable stimulus intensity parameters that can be dynamically modified based on individual subject requirements. The controller allows programming of varying light and sound intensities, enabling adaptation to each subject's sensory thresholds and preferences while maintaining simple operation through automated control algorithms

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method and device provide a synergistic effect in promoting sleep by entraining brain oscillations into a lower frequency range associated with sleepiness, offering a non-pharmacologic alternative to traditional treatments.

Implementation Method 1

The method and device provide a synergistic effect in promoting sleep by entraining brain oscillations into a lower frequency range associated with sleepiness

Methodology Applied
Scientific EffectEntrainment: Entrainment

Implementation Method 2

the system also includes at least one EEG electrode configured for measuring brain oscillations of the subject

Methodology Applied
Scientific EffectElectroencephalography:

Data Source

PatentUS20220134051A1Multimodal sensory stimulation
Publication Date: 2022.05.05 THE UNIVERSITY OF IOWA RESEARCH
  • US20220134051A1 patent drawing

AI summary

A multimodal sensory device for promoting sleep in a subject, including a first sensory delivery component, a second sensory delivery component, and a controller module. The sensory device wherein the first and second sensory delivery components are constructed and arranged for delivering a first and second sensory stimuli to the subject and the controller is constructed and arranged to deliver the first and second sensory stimuli at a synchronized frequency. A method for promoting sleep in a subject including delivering to the subject at least one sensory stimuli at a frequency of between about 1 and 60 hz.